A complex bearing TSPO PIGA ligand coordinated to the [Au(PEt(3))](+) pharmacophore is highly cytotoxic against ovarian cancer cells

Auranofin ([1-(thio-κS)-β-d-glucopyranose-2,3,4,6-tetraacetato](triethylphosphine)-gold) is a leading gold-based drug clinically used to treat arthritis. In the last years, it entered various drug reprofiling programs, and it has been found promising against various forms of tumor, including ovarian...

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Detalles Bibliográficos
Autores principales: Chiaverini, Lorenzo, Baglini, Emma, Mannelli, Michele, Poggetti, Valeria, Da Settimo, Federico, Taliani, Sabrina, Gamberi, Tania, Barresi, Elisabetta, La Mendola, Diego, Marzo, Tiziano
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Netherlands 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10545567/
https://www.ncbi.nlm.nih.gov/pubmed/36869967
http://dx.doi.org/10.1007/s10534-023-00496-8

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