FGF10 mitigates doxorubicin-induced myocardial toxicity in mice via activation of FGFR2b/PHLDA1/AKT axis

Doxorubicin is a common chemotherapeutic agent in clinic, but myocardial toxicity limits its use. Fibroblast growth factor (FGF) 10, a multifunctional paracrine growth factor, plays diverse roles in embryonic and postnatal heart development as well as in cardiac regeneration and repair. In this stud...

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Detalles Bibliográficos
Autores principales: Zhou, De-pu, Deng, Lian-cheng, Feng, Xiao, Xu, Hui-jing, Tian, Ye, Yang, Wei-wei, Zeng, Ping-ping, Zou, Li-hui, Yan, Xi-hua, Zhu, Xia-yan, Shu, Dan-hua, Guo, Qiang, Huang, Xiao-ying, Bellusci, Saverio, Lou, Zhenkun, Li, Xiao-kun, Zhang, Jin-San
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Nature Singapore 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10545682/
https://www.ncbi.nlm.nih.gov/pubmed/37225844
http://dx.doi.org/10.1038/s41401-023-01101-x

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