Fitness cost associated with cell phenotypic switching drives population diversification dynamics and controllability

Isogenic cell populations can cope with stress conditions by switching to alternative phenotypes. Even if it can lead to increased fitness in a natural context, this feature is typically unwanted for a range of applications (e.g., bioproduction, synthetic biology, and biomedicine) where it tends to...

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Detalles Bibliográficos
Autores principales: Henrion, Lucas, Martinez, Juan Andres, Vandenbroucke, Vincent, Delvenne, Mathéo, Telek, Samuel, Zicler, Andrew, Grünberger, Alexander, Delvigne, Frank
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10545768/
https://www.ncbi.nlm.nih.gov/pubmed/37783690
http://dx.doi.org/10.1038/s41467-023-41917-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10545768/
https://www.ncbi.nlm.nih.gov/pubmed/37783690
http://dx.doi.org/10.1038/s41467-023-41917-z

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