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Association of high intra-patient variability in tacrolimus exposure with calcineurin inhibitor nephrotoxicity in kidney transplantation
Tacrolimus intra-patient variability (IPV) is a novel predictive marker for long-term kidney transplantation outcomes. We examined the association between IPV and calcineurin inhibitor (CNI) nephrotoxicity and the impact of pharmacogenes on CNI nephrotoxicity and IPV. Among kidney transplant recipie...
Autores principales: | Kim, Hyokee, Han, Ahram, Ahn, Sanghyun, Min, Seung-Kee, Ha, Jongwon, Min, Sangil |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10545770/ https://www.ncbi.nlm.nih.gov/pubmed/37783764 http://dx.doi.org/10.1038/s41598-023-43755-x |
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