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Memory consolidation during sleep involves context reinstatement in humans
New memories are not quarantined from each other when first encoded; rather, they are interlinked with memories that were encoded in temporal proximity or that share semantic features. By selectively biasing memory processing during sleep, here we test whether context influences sleep consolidation....
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10545811/ https://www.ncbi.nlm.nih.gov/pubmed/37014750 http://dx.doi.org/10.1016/j.celrep.2023.112331 |
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author | Schechtman, Eitan Heilberg, Julia Paller, Ken A. |
author_facet | Schechtman, Eitan Heilberg, Julia Paller, Ken A. |
author_sort | Schechtman, Eitan |
collection | PubMed |
description | New memories are not quarantined from each other when first encoded; rather, they are interlinked with memories that were encoded in temporal proximity or that share semantic features. By selectively biasing memory processing during sleep, here we test whether context influences sleep consolidation. Participants first formed 18 idiosyncratic narratives, each linking four objects together. Before sleep, they also memorized an on-screen position for each object. During sleep, 12 object-specific sounds were unobtrusively presented, thereby cuing the corresponding spatial memories and impacting spatial recall as a function of initial memory strength. As hypothesized, we find that recall for non-cued objects contextually linked with cued objects also changed. Post-cue electrophysiological responses suggest that activity in the sigma band supports context reinstatement and predicts context-related memory benefits. Concurrently, context-specific electrophysiological activity patterns emerge during sleep. We conclude that reactivation of individual memories during sleep evokes reinstatement of their context, thereby impacting consolidation of associated knowledge. |
format | Online Article Text |
id | pubmed-10545811 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
record_format | MEDLINE/PubMed |
spelling | pubmed-105458112023-10-23 Memory consolidation during sleep involves context reinstatement in humans Schechtman, Eitan Heilberg, Julia Paller, Ken A. Cell Rep Article New memories are not quarantined from each other when first encoded; rather, they are interlinked with memories that were encoded in temporal proximity or that share semantic features. By selectively biasing memory processing during sleep, here we test whether context influences sleep consolidation. Participants first formed 18 idiosyncratic narratives, each linking four objects together. Before sleep, they also memorized an on-screen position for each object. During sleep, 12 object-specific sounds were unobtrusively presented, thereby cuing the corresponding spatial memories and impacting spatial recall as a function of initial memory strength. As hypothesized, we find that recall for non-cued objects contextually linked with cued objects also changed. Post-cue electrophysiological responses suggest that activity in the sigma band supports context reinstatement and predicts context-related memory benefits. Concurrently, context-specific electrophysiological activity patterns emerge during sleep. We conclude that reactivation of individual memories during sleep evokes reinstatement of their context, thereby impacting consolidation of associated knowledge. 2023-04-25 2023-04-03 /pmc/articles/PMC10545811/ /pubmed/37014750 http://dx.doi.org/10.1016/j.celrep.2023.112331 Text en https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/ (https://creativecommons.org/licenses/by-nc-nd/4.0/) ). |
spellingShingle | Article Schechtman, Eitan Heilberg, Julia Paller, Ken A. Memory consolidation during sleep involves context reinstatement in humans |
title | Memory consolidation during sleep involves context reinstatement in humans |
title_full | Memory consolidation during sleep involves context reinstatement in humans |
title_fullStr | Memory consolidation during sleep involves context reinstatement in humans |
title_full_unstemmed | Memory consolidation during sleep involves context reinstatement in humans |
title_short | Memory consolidation during sleep involves context reinstatement in humans |
title_sort | memory consolidation during sleep involves context reinstatement in humans |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10545811/ https://www.ncbi.nlm.nih.gov/pubmed/37014750 http://dx.doi.org/10.1016/j.celrep.2023.112331 |
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