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Trajectory reconstruction identifies dysregulation of perinatal maturation programs in pluripotent stem cell-derived cardiomyocytes

A limitation in the application of pluripotent stem cell-derived cardiomyocytes (PSC-CMs) is the failure of these cells to achieve full functional maturity. The mechanisms by which directed differentiation differs from endogenous development, leading to consequent PSC-CM maturation arrest, remain un...

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Detalles Bibliográficos
Autores principales:	Kannan, Suraj, Miyamoto, Matthew, Zhu, Renjun, Lynott, Michaela, Guo, Jason, Chen, Elaine Zhelan, Colas, Alexandre R., Lin, Brian Leei, Kwon, Chulan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10545814/ https://www.ncbi.nlm.nih.gov/pubmed/37014753 http://dx.doi.org/10.1016/j.celrep.2023.112330

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