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Azilsartan inhibits inflammation-triggered bone resorption and osteoclastogenesis in vivo via suppression of TNF-α expression in macrophages

INTRODUCTION: Hypertension is a major risk factor for cardiovascular disease (CVD) and is associated with increased bone loss due to excessive activity of the local renin-angiotensin system (RAS). Angiotensinogen/Angiotensin (ANG) II/Angiotensin II type 1 receptor (AT1R) axis is considered as the co...

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Detalles Bibliográficos
Autores principales:	Fan, Ziqiu, Kitaura, Hideki, Ren, Jiayi, Ohori, Fumitoshi, Noguchi, Takahiro, Marahleh, Aseel, Ma, Jinghan, Kanou, Kayoko, Miura, Mariko, Narita, Kohei, Lin, Angyi, Mizoguchi, Itaru
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2023
Materias:	Endocrinology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10545845/ https://www.ncbi.nlm.nih.gov/pubmed/37795376 http://dx.doi.org/10.3389/fendo.2023.1207502

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