Hybrid structural modeling of alloantibody binding to human leukocyte antigen with rapid and reproducible cross-linking mass spectrometry

Alloantibody recognition of donor human leukocyte antigen (HLA) is associated with poor clinical transplantation outcomes. However, the molecular and structural basis for the alloantibody-HLA interaction is not well understood. Here, we used a hybrid structural modeling approach on a previously stud...

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Detalles Bibliográficos
Autores principales: Ser, Zheng, Gu, Yue, Yap, Jiawei, Lim, Yan Ting, Wang, Shi Mei, Hamidinia, Maryam, Murali, Tanusya Murali, Kumar, Ragini, Gascoigne, Nicholas RJ., MacAry, Paul A., Sobota, Radoslaw M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10545907/
https://www.ncbi.nlm.nih.gov/pubmed/37751693
http://dx.doi.org/10.1016/j.crmeth.2023.100569

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