Cargando…

Comparison of Gut Microbiome in Neonates Born by Caesarean Section and Vaginal Seeding with Gut Microbiomes of Neonates Born by Caesarean Section Without Vaginal Seeding and Neonates Born by Vaginal Delivery

BACKGROUND: Pregnancy is an admirable biological process, resulting in significant changes in many of the body's normal systems so that they can support the development of the fetus. These changes involve hormonal changes, weight gain, immune system regulation, and others that need to be synchr...

Descripción completa

Detalles Bibliográficos
Autores principales: Anthoulaki, Xanthi, Oikonomou, Efthimios, Bothou, Anastasia, Papanikolopoulou, Stavroula, Nikolettos, Konstantinos, Damaskos, Christos, Garbis, Nikolaos, Kyriakou, Dimitrios, Nalbanti, Theopi, Iatrakis, Georgios, Nikolettos, Nikolaos, Tsikouras, Panagiotis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AVICENA, d.o.o., Sarajevo 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10545928/
https://www.ncbi.nlm.nih.gov/pubmed/37795168
http://dx.doi.org/10.5455/msm.2023.35.234-243
_version_ 1785114768778985472
author Anthoulaki, Xanthi
Oikonomou, Efthimios
Bothou, Anastasia
Papanikolopoulou, Stavroula
Nikolettos, Konstantinos
Damaskos, Christos
Garbis, Nikolaos
Kyriakou, Dimitrios
Nalbanti, Theopi
Iatrakis, Georgios
Nikolettos, Nikolaos
Tsikouras, Panagiotis
author_facet Anthoulaki, Xanthi
Oikonomou, Efthimios
Bothou, Anastasia
Papanikolopoulou, Stavroula
Nikolettos, Konstantinos
Damaskos, Christos
Garbis, Nikolaos
Kyriakou, Dimitrios
Nalbanti, Theopi
Iatrakis, Georgios
Nikolettos, Nikolaos
Tsikouras, Panagiotis
author_sort Anthoulaki, Xanthi
collection PubMed
description BACKGROUND: Pregnancy is an admirable biological process, resulting in significant changes in many of the body's normal systems so that they can support the development of the fetus. These changes involve hormonal changes, weight gain, immune system regulation, and others that need to be synchronized to maintain both maternal and fetal health. OBJECTIVE: The purpose of this study was to compare gut microbiome in neonates born by caesarean section and vaginal seeding with gut microbiomes of neonates born by caesarean section without vaginal seeding and neonates born by vaginal delivery. METHODS: In Democritus University of Thrace, from 2019 to 2022, gut microbiomes were compared for three groups of neonates. Group A included 110 neonates born by CS who underwent vaginal seeding, group B included 85 neonates born by CS without vaginal seeding and group C included 95 neonates born by vaginal delivery. RESULTS: Vaginal seeding in neonates born with CS resulted in gut microbiome which was similar to the gut microbiome of neonates born by vaginal delivery (including lactobacillus species and bacteroides). On the contrary, gut microbiome of neonates born by CS without vaginal seeding was “limited”. CONCLUSION: According to our findings, vaginal seeding alters the gut microbiome of the neonates born with CS. However, there is a need for further investigation to prove its efficacy and its safety for the neonate.
format Online
Article
Text
id pubmed-10545928
institution National Center for Biotechnology Information
language English
publishDate 2023
publisher AVICENA, d.o.o., Sarajevo
record_format MEDLINE/PubMed
spelling pubmed-105459282023-10-04 Comparison of Gut Microbiome in Neonates Born by Caesarean Section and Vaginal Seeding with Gut Microbiomes of Neonates Born by Caesarean Section Without Vaginal Seeding and Neonates Born by Vaginal Delivery Anthoulaki, Xanthi Oikonomou, Efthimios Bothou, Anastasia Papanikolopoulou, Stavroula Nikolettos, Konstantinos Damaskos, Christos Garbis, Nikolaos Kyriakou, Dimitrios Nalbanti, Theopi Iatrakis, Georgios Nikolettos, Nikolaos Tsikouras, Panagiotis Mater Sociomed Original Paper BACKGROUND: Pregnancy is an admirable biological process, resulting in significant changes in many of the body's normal systems so that they can support the development of the fetus. These changes involve hormonal changes, weight gain, immune system regulation, and others that need to be synchronized to maintain both maternal and fetal health. OBJECTIVE: The purpose of this study was to compare gut microbiome in neonates born by caesarean section and vaginal seeding with gut microbiomes of neonates born by caesarean section without vaginal seeding and neonates born by vaginal delivery. METHODS: In Democritus University of Thrace, from 2019 to 2022, gut microbiomes were compared for three groups of neonates. Group A included 110 neonates born by CS who underwent vaginal seeding, group B included 85 neonates born by CS without vaginal seeding and group C included 95 neonates born by vaginal delivery. RESULTS: Vaginal seeding in neonates born with CS resulted in gut microbiome which was similar to the gut microbiome of neonates born by vaginal delivery (including lactobacillus species and bacteroides). On the contrary, gut microbiome of neonates born by CS without vaginal seeding was “limited”. CONCLUSION: According to our findings, vaginal seeding alters the gut microbiome of the neonates born with CS. However, there is a need for further investigation to prove its efficacy and its safety for the neonate. AVICENA, d.o.o., Sarajevo 2023-09 /pmc/articles/PMC10545928/ /pubmed/37795168 http://dx.doi.org/10.5455/msm.2023.35.234-243 Text en © 2023 Xanthi Anthoulaki, Efthimios Oikonomou, Anastasia Bothou Stavroula Papanikolopoulou, Konstantinos Nikolettos, Christos Damaskos, Nikolaos Garbis, Dimitrios Kyriakou, Theopi Nalbanti, Georgios Iatrakis, Nikolaos Nikolettos, Panagiotis Tsikouras https://creativecommons.org/licenses/by-nc/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/ (https://creativecommons.org/licenses/by-nc/4.0/) ) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Paper
Anthoulaki, Xanthi
Oikonomou, Efthimios
Bothou, Anastasia
Papanikolopoulou, Stavroula
Nikolettos, Konstantinos
Damaskos, Christos
Garbis, Nikolaos
Kyriakou, Dimitrios
Nalbanti, Theopi
Iatrakis, Georgios
Nikolettos, Nikolaos
Tsikouras, Panagiotis
Comparison of Gut Microbiome in Neonates Born by Caesarean Section and Vaginal Seeding with Gut Microbiomes of Neonates Born by Caesarean Section Without Vaginal Seeding and Neonates Born by Vaginal Delivery
title Comparison of Gut Microbiome in Neonates Born by Caesarean Section and Vaginal Seeding with Gut Microbiomes of Neonates Born by Caesarean Section Without Vaginal Seeding and Neonates Born by Vaginal Delivery
title_full Comparison of Gut Microbiome in Neonates Born by Caesarean Section and Vaginal Seeding with Gut Microbiomes of Neonates Born by Caesarean Section Without Vaginal Seeding and Neonates Born by Vaginal Delivery
title_fullStr Comparison of Gut Microbiome in Neonates Born by Caesarean Section and Vaginal Seeding with Gut Microbiomes of Neonates Born by Caesarean Section Without Vaginal Seeding and Neonates Born by Vaginal Delivery
title_full_unstemmed Comparison of Gut Microbiome in Neonates Born by Caesarean Section and Vaginal Seeding with Gut Microbiomes of Neonates Born by Caesarean Section Without Vaginal Seeding and Neonates Born by Vaginal Delivery
title_short Comparison of Gut Microbiome in Neonates Born by Caesarean Section and Vaginal Seeding with Gut Microbiomes of Neonates Born by Caesarean Section Without Vaginal Seeding and Neonates Born by Vaginal Delivery
title_sort comparison of gut microbiome in neonates born by caesarean section and vaginal seeding with gut microbiomes of neonates born by caesarean section without vaginal seeding and neonates born by vaginal delivery
topic Original Paper
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10545928/
https://www.ncbi.nlm.nih.gov/pubmed/37795168
http://dx.doi.org/10.5455/msm.2023.35.234-243
work_keys_str_mv AT anthoulakixanthi comparisonofgutmicrobiomeinneonatesbornbycaesareansectionandvaginalseedingwithgutmicrobiomesofneonatesbornbycaesareansectionwithoutvaginalseedingandneonatesbornbyvaginaldelivery
AT oikonomouefthimios comparisonofgutmicrobiomeinneonatesbornbycaesareansectionandvaginalseedingwithgutmicrobiomesofneonatesbornbycaesareansectionwithoutvaginalseedingandneonatesbornbyvaginaldelivery
AT bothouanastasia comparisonofgutmicrobiomeinneonatesbornbycaesareansectionandvaginalseedingwithgutmicrobiomesofneonatesbornbycaesareansectionwithoutvaginalseedingandneonatesbornbyvaginaldelivery
AT papanikolopouloustavroula comparisonofgutmicrobiomeinneonatesbornbycaesareansectionandvaginalseedingwithgutmicrobiomesofneonatesbornbycaesareansectionwithoutvaginalseedingandneonatesbornbyvaginaldelivery
AT nikolettoskonstantinos comparisonofgutmicrobiomeinneonatesbornbycaesareansectionandvaginalseedingwithgutmicrobiomesofneonatesbornbycaesareansectionwithoutvaginalseedingandneonatesbornbyvaginaldelivery
AT damaskoschristos comparisonofgutmicrobiomeinneonatesbornbycaesareansectionandvaginalseedingwithgutmicrobiomesofneonatesbornbycaesareansectionwithoutvaginalseedingandneonatesbornbyvaginaldelivery
AT garbisnikolaos comparisonofgutmicrobiomeinneonatesbornbycaesareansectionandvaginalseedingwithgutmicrobiomesofneonatesbornbycaesareansectionwithoutvaginalseedingandneonatesbornbyvaginaldelivery
AT kyriakoudimitrios comparisonofgutmicrobiomeinneonatesbornbycaesareansectionandvaginalseedingwithgutmicrobiomesofneonatesbornbycaesareansectionwithoutvaginalseedingandneonatesbornbyvaginaldelivery
AT nalbantitheopi comparisonofgutmicrobiomeinneonatesbornbycaesareansectionandvaginalseedingwithgutmicrobiomesofneonatesbornbycaesareansectionwithoutvaginalseedingandneonatesbornbyvaginaldelivery
AT iatrakisgeorgios comparisonofgutmicrobiomeinneonatesbornbycaesareansectionandvaginalseedingwithgutmicrobiomesofneonatesbornbycaesareansectionwithoutvaginalseedingandneonatesbornbyvaginaldelivery
AT nikolettosnikolaos comparisonofgutmicrobiomeinneonatesbornbycaesareansectionandvaginalseedingwithgutmicrobiomesofneonatesbornbycaesareansectionwithoutvaginalseedingandneonatesbornbyvaginaldelivery
AT tsikouraspanagiotis comparisonofgutmicrobiomeinneonatesbornbycaesareansectionandvaginalseedingwithgutmicrobiomesofneonatesbornbycaesareansectionwithoutvaginalseedingandneonatesbornbyvaginaldelivery