Cargando…

SpecHLA enables full-resolution HLA typing from sequencing data

Reconstructing diploid sequences of human leukocyte antigen (HLA) genes, i.e., full-resolution HLA typing, from sequencing data is challenging. The high homogeneity across HLA genes and the high heterogeneity within HLA alleles complicate the identification of genomic source loci for sequencing read...

Descripción completa

Detalles Bibliográficos
Autores principales: Wang, Shuai, Wang, Mengyao, Chen, Lingxi, Pan, Guangze, Wang, Yanfei, Li, Shuai Cheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10545945/
https://www.ncbi.nlm.nih.gov/pubmed/37714157
http://dx.doi.org/10.1016/j.crmeth.2023.100589

Ejemplares similares