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Integration of a perfusion reactor and continuous precipitation in an entirely membrane‐based process for antibody capture

Continuous precipitation coupled with continuous tangential flow filtration is a cost‐effective alternative for the capture of recombinant antibodies from crude cell culture supernatant. The removal of surge tanks between unit operations, by the adoption of tubular reactors, maintains a continuous h...

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Detalles Bibliográficos
Autores principales: Recanati, Gabriele, Pappenreiter, Magdalena, Gstoettner, Christoph, Scheidl, Patrick, Vega, Elena Domínguez, Sissolak, Bernhard, Jungbauer, Alois
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10545976/
https://www.ncbi.nlm.nih.gov/pubmed/37795344
http://dx.doi.org/10.1002/elsc.202300219