Cargando…
Integration of a perfusion reactor and continuous precipitation in an entirely membrane‐based process for antibody capture
Continuous precipitation coupled with continuous tangential flow filtration is a cost‐effective alternative for the capture of recombinant antibodies from crude cell culture supernatant. The removal of surge tanks between unit operations, by the adoption of tubular reactors, maintains a continuous h...
Autores principales: | Recanati, Gabriele, Pappenreiter, Magdalena, Gstoettner, Christoph, Scheidl, Patrick, Vega, Elena Domínguez, Sissolak, Bernhard, Jungbauer, Alois |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10545976/ https://www.ncbi.nlm.nih.gov/pubmed/37795344 http://dx.doi.org/10.1002/elsc.202300219 |
Ejemplares similares
-
Model predictive control for steady-state performance in integrated continuous bioprocesses
por: Pappenreiter, Magdalena, et al.
Publicado: (2022) -
Continuous capture of recombinant antibodies by ZnCl(2) precipitation without polyethylene glycol
por: Dutra, Gregory, et al.
Publicado: (2020) -
Oxygen Uptake Rate Soft-Sensing via Dynamic k(L)a Computation: Cell Volume and Metabolic Transition Prediction in Mammalian Bioprocesses
por: Pappenreiter, Magdalena, et al.
Publicado: (2019) -
Mid‐manufacturing storage: Antibody stability after chromatography and precipitation based capture steps
por: Krepper, Walpurga, et al.
Publicado: (2019) -
Continuous integrated antibody precipitation with two‐stage tangential flow microfiltration enables constant mass flow
por: Burgstaller, Daniel, et al.
Publicado: (2019)