Cargando…
The landscape of MHC-presented phosphopeptides yields actionable shared tumor antigens for cancer immunotherapy across multiple HLA alleles
BACKGROUND: Certain phosphorylated peptides are differentially presented by major histocompatibility complex (MHC) molecules on cancer cells characterized by aberrant phosphorylation. Phosphopeptides presented in complex with the human leukocyte antigen HLA-A*02:01 provide a stability advantage over...
Autores principales: | Molvi, Zaki, Klatt, Martin G, Dao, Tao, Urraca, Jessica, Scheinberg, David A, O'Reilly, Richard J |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BMJ Publishing Group
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10546156/ https://www.ncbi.nlm.nih.gov/pubmed/37775115 http://dx.doi.org/10.1136/jitc-2023-006889 |
Ejemplares similares
-
The landscape of MHC-presented phosphopeptides yields actionable shared tumor antigens for cancer immunotherapy across multiple HLA alleles
por: Molvi, Zaki, et al.
Publicado: (2023) -
Empirical and Rational Design of T Cell Receptor-Based Immunotherapies
por: Jones, Heather F., et al.
Publicado: (2021) -
HLA Ligand Atlas: a benign reference of HLA-presented peptides to improve T-cell-based cancer immunotherapy
por: Marcu, Ana, et al.
Publicado: (2021) -
Solving an MHC allele–specific bias in the reported immunopeptidome
por: Klatt, Martin G., et al.
Publicado: (2020) -
A TCR mimic monoclonal antibody reactive with the “public” phospho-neoantigen pIRS2/HLA-A*02:01 complex
por: Dao, Tao, et al.
Publicado: (2022)