The landscape of MHC-presented phosphopeptides yields actionable shared tumor antigens for cancer immunotherapy across multiple HLA alleles

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BACKGROUND: Certain phosphorylated peptides are differentially presented by major histocompatibility complex (MHC) molecules on cancer cells characterized by aberrant phosphorylation. Phosphopeptides presented in complex with the human leukocyte antigen HLA-A*02:01 provide a stability advantage over...

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Detalles Bibliográficos
Autores principales: Molvi, Zaki, Klatt, Martin G, Dao, Tao, Urraca, Jessica, Scheinberg, David A, O'Reilly, Richard J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2023
Materias:
Basic Tumor Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10546156/
https://www.ncbi.nlm.nih.gov/pubmed/37775115
http://dx.doi.org/10.1136/jitc-2023-006889
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