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Genome-wide CRISPR screens and their applications in infectious disease

Inactivation or targeted disruption of a gene provides clues to assess the function of the gene in many cellular processes. Knockdown or knocking out a gene has been widely used for this purpose. However, recently CRISPR mediated genome editing has taken over the knockout/knockdown system with more...

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Detalles Bibliográficos
Autores principales: Srivastava, Kaveri, Pandit, Bhaswati
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10546192/
https://www.ncbi.nlm.nih.gov/pubmed/37794981
http://dx.doi.org/10.3389/fgeed.2023.1243731