Cigarette smoke restricts the ability of mesenchymal cells to support lung epithelial organoid formation

Adequate lung epithelial repair relies on supportive interactions within the epithelial niche, including interactions with WNT-responsive fibroblasts. In fibroblasts from patients with chronic obstructive pulmonary disease (COPD) or upon in vitro cigarette smoke exposure, Wnt/β-catenin signalling is...

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Detalles Bibliográficos
Autores principales: Khedoe, P. P. S. J., van Schadewijk, W. A. A. M., Schwiening, M., Ng-Blichtfeldt, J. P., Marciniak, S. J., Stolk, J., Gosens, R., Hiemstra, P. S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Cell and Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10546195/
https://www.ncbi.nlm.nih.gov/pubmed/37795260
http://dx.doi.org/10.3389/fcell.2023.1165581

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