Metformin targets intestinal immune system signaling pathways in a high-fat diet-induced mouse model of obesity and insulin resistance

INTRODUCTION: Research findings of the past decade have highlighted the gut as the main site of action of the oral antihyperglycemic agent metformin despite its pharmacological role in the liver. Extensive evidence supports metformin’s modulatory effect on the composition and function of gut microbi...

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Detalles Bibliográficos
Autores principales: Brīvība, Monta, Silamiķele, Laila, Kalniņa, Ineta, Silamiķelis, Ivars, Birzniece, Līga, Ansone, Laura, Jagare, Lauma, Elbere, Ilze, Kloviņš, Jānis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Endocrinology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10546317/
https://www.ncbi.nlm.nih.gov/pubmed/37795356
http://dx.doi.org/10.3389/fendo.2023.1232143

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10546317/
https://www.ncbi.nlm.nih.gov/pubmed/37795356
http://dx.doi.org/10.3389/fendo.2023.1232143

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