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Histidine-rich glycoprotein attenuates catheter thrombosis

Factor XII (FXII) knockdown attenuates catheter thrombosis in rabbits. Because histidine-rich glycoprotein (HRG) modulates FXIIa activity, we hypothesized that HRG depletion would promote catheter thrombosis. To test this, rabbits were given either antisense oligonucleotides (ASOs) against HRG or FX...

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Detalles Bibliográficos
Autores principales: Malik, Rida A., Liao, Peng, Zhou, Ji, Hussain, Rawaa, Fredenburgh, James C., Hettrick, Lisa, Revenko, Alexey S., Weitz, Jeffrey I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society of Hematology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10546346/
https://www.ncbi.nlm.nih.gov/pubmed/37042966
http://dx.doi.org/10.1182/bloodadvances.2022009236