Mechanism of multidrug resistance to chemotherapy mediated by P-glycoprotein (Review)

Multidrug resistance (MDR) seriously limits the clinical application of chemotherapy. A mechanism underlying MDR is the overexpression of efflux transporters associated with chemotherapeutic drugs. P-glycoprotein (P-gp) is an ATP-binding cassette (ABC) transporter, which promotes MDR by pumping out...

Descripción completa

Detalles Bibliográficos
Autores principales: Tian, Yichen, Lei, Yongrong, Wang, Yani, Lai, Jiejuan, Wang, Jianhua, Xia, Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2023
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10546381/
https://www.ncbi.nlm.nih.gov/pubmed/37654171
http://dx.doi.org/10.3892/ijo.2023.5567

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10546381/
https://www.ncbi.nlm.nih.gov/pubmed/37654171
http://dx.doi.org/10.3892/ijo.2023.5567

Ejemplares similares