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Mechanism of multidrug resistance to chemotherapy mediated by P-glycoprotein (Review)

Multidrug resistance (MDR) seriously limits the clinical application of chemotherapy. A mechanism underlying MDR is the overexpression of efflux transporters associated with chemotherapeutic drugs. P-glycoprotein (P-gp) is an ATP-binding cassette (ABC) transporter, which promotes MDR by pumping out...

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Detalles Bibliográficos
Autores principales:	Tian, Yichen, Lei, Yongrong, Wang, Yani, Lai, Jiejuan, Wang, Jianhua, Xia, Feng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2023
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10546381/ https://www.ncbi.nlm.nih.gov/pubmed/37654171 http://dx.doi.org/10.3892/ijo.2023.5567

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