Cargando…

Expanded Hemodialysis ameliorates uremia-induced impairment of vasculoprotective KLF2 and concomitant proinflammatory priming of endothelial cells through an ERK/AP1/cFOS-dependent mechanism

AIMS: Expanded hemodialysis (HDx) therapy with improved molecular cut-off dialyzers exerts beneficial effects on lowering uremia-associated chronic systemic microinflammation, a driver of endothelial dysfunction and cardiovascular disease (CVD) in hemodialysis (HD) patients with end-stage renal dise...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhao, Hongfan, Wu, Dashan, Gyamfi, Michael Adu, Wang, Pinchao, Luecht, Christian, Pfefferkorn, Anna Maria, Ashraf, Muhammad Imtiaz, Kamhieh-Milz, Julian, Witowski, Janusz, Dragun, Duska, Budde, Klemens, Schindler, Ralf, Zickler, Daniel, Moll, Guido, Catar, Rusan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2023
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10546407/ https://www.ncbi.nlm.nih.gov/pubmed/37795100 http://dx.doi.org/10.3389/fimmu.2023.1209464

Ejemplares similares

Expanded Hemodialysis Therapy Ameliorates Uremia-Induced Systemic Microinflammation and Endothelial Dysfunction by Modulating VEGF, TNF-α and AP-1 Signaling
por: Catar, Rusan, et al.
Publicado: (2021)

Transcriptional Regulation of Thrombin-Induced Endothelial VEGF Induction and Proangiogenic Response
por: Catar, Rusan, et al.
Publicado: (2021)

Native and Oxidized Low-Density Lipoproteins Increase the Expression of the LDL Receptor and the LOX-1 Receptor, Respectively, in Arterial Endothelial Cells
por: Catar, Rusan, et al.
Publicado: (2022)

Autoantibodies from patients with kidney allograft vasculopathy stimulate a proinflammatory switch in endothelial cells and monocytes mediated via GPCR-directed PAR1-TNF-α signaling
por: Moll, Guido, et al.
Publicado: (2023)

IL-17 in Peritoneal Dialysis-Associated Inflammation and Angiogenesis: Conclusions and Perspectives
por: Witowski, Janusz, et al.
Publicado: (2018)

Angiogenic Role of Mesothelium-Derived Chemokine CXCL1 During Unfavorable Peritoneal Tissue Remodeling in Patients Receiving Peritoneal Dialysis as Renal Replacement Therapy
por: Catar, Rusan Ali, et al.
Publicado: (2022)

Nailfold Videocapillaroscopy for Non-Invasive Assessment of Microcirculation and Prognostic Correlation with Endothelial Dysfunction, Cardiovascular Risk Factors, and Non-HLA Antibodies in Heart Transplant Recipients: A Pilot Study
por: Sikorska, Dorota, et al.
Publicado: (2023)

Autoantibodies from Patients with Scleroderma Renal Crisis Promote PAR-1 Receptor Activation and IL-6 Production in Endothelial Cells
por: Simon, Michèle, et al.
Publicado: (2021)

Regulation of Chemokine CCL5 Synthesis in Human Peritoneal Fibroblasts: A Key Role of IFN-γ
por: Kawka, Edyta, et al.
Publicado: (2014)

cFOS as a biomarker of activity maturation in the hippocampal formation
por: Pompeiano, Maria, et al.
Publicado: (2023)

A cFos activation map of remote fear memory attenuation
por: Silva, Bianca A., et al.
Publicado: (2018)

Molecular Effects of Auto-Antibodies on Angiotensin II Type 1 Receptor Signaling and Cell Proliferation
por: Philippe, Aurélie, et al.
Publicado: (2022)

Autoantibodies Targeting AT(1)- and ET(A)-Receptors Link Endothelial Proliferation and Coagulation via Ets-1 Transcription Factor
por: Catar, Rusan, et al.
Publicado: (2021)

ΔFosB accumulation in hippocampal granule cells drives cFos pattern separation during spatial learning
por: Lamothe-Molina, Paul J., et al.
Publicado: (2022)

Time units for learning involving maintenance of system-wide cFos expression in neuronal assemblies
por: Chowdhury, Ananya, et al.
Publicado: (2018)

Toxoplasma and Eimeria co-opt the host cFos expression for intracellular development in mammalian cells
por: Ren, Bingjian, et al.
Publicado: (2021)

Intrinsic Deregulation of Vascular Smooth Muscle and Myofibroblast Differentiation in Mesenchymal Stromal Cells from Patients with Systemic Sclerosis
por: Hegner, Björn, et al.
Publicado: (2016)

Truncated and Helix-Constrained Peptides with High Affinity and Specificity for the cFos Coiled-Coil of AP-1
por: Rao, Tara, et al.
Publicado: (2013)

Actions of Agonists and Antagonists of the ghrelin/GHS-R Pathway on GH Secretion, Appetite, and cFos Activity
por: Hassouna, Rim, et al.
Publicado: (2013)

cFOS expression in the prefrontal cortex correlates with altered cerebral metabolism in developing germ-free mice
por: Pate, Trinity, et al.
Publicado: (2023)

17ß-Estradiol Regulates mTORC2 Sensitivity to Rapamycin in Adaptive Cardiac Remodeling
por: Kusch, Angelika, et al.
Publicado: (2015)

Preclinical Toxicity Evaluation of Clinical Grade Placenta-Derived Decidua Stromal Cells
por: Sadeghi, Behnam, et al.
Publicado: (2019)

Propofol induces MAPK/ERK cascade dependant expression of cFos and Egr-1 in rat hippocampal slices
por: Kidambi, Srivatsan, et al.
Publicado: (2010)

Lesions of the Fasciculus Retroflexus Alter Footshock-Induced cFos Expression in the Mesopontine Rostromedial Tegmental Area of Rats
por: Brown, Paul Leon, et al.
Publicado: (2013)

Expression of cFos and brain-derived neurotrophic factor in cortex and hippocampus of ethanol-withdrawn male and female rats
por: Alele, Paul E., et al.
Publicado: (2013)

Author Correction: Time units for learning involving maintenance of system-wide cFos expression in neuronal assemblies
por: Chowdhury, Ananya, et al.
Publicado: (2019)

cFOS-SOX9 Axis Reprograms Bone Marrow-Derived Mesenchymal Stem Cells into Chondroblastic Osteosarcoma
por: He, Yunlong, et al.
Publicado: (2017)

The Role of Adipose Tissue in the Pathogenesis and Therapeutic Outcomes of Inflammatory Bowel Disease
por: Eder, Piotr, et al.
Publicado: (2019)

NMDA Receptor Signaling Mediates cFos Expression via Top2β-Induced DSBs in Glioblastoma Cells
por: Lutz, Henrik, et al.
Publicado: (2019)

Disruption of PAK3 Signaling in Social Interaction Induced cFos Positive Cells Impairs Social Recognition Memory
por: Zhou, Susan, et al.
Publicado: (2021)

Quanty-cFOS, a Novel ImageJ/Fiji Algorithm for Automated Counting of Immunoreactive Cells in Tissue Sections
por: Beretta, Carlo Antonio, et al.
Publicado: (2023)

Selection and Characterization of a DNA Aptamer That Can Discriminate between cJun/cJun and cJun/cFos
por: Walters, Ryan D., et al.
Publicado: (2014)

Hydrogen sulfide as a vasculoprotective factor
por: Streeter, Eloise, et al.
Publicado: (2013)

Vasculoprotective Effects of Vildagliptin. Focus on Atherogenesis
por: Wiciński, Michał, et al.
Publicado: (2020)

Vasculoprotective Effects of Pomegranate (Punica granatum L.)
por: Wang, Dongdong, et al.
Publicado: (2018)

Impact of Adolescent Intermittent Ethanol Exposure on Social Investigation, Social Preference, and Neuronal Activation in cFos-LacZ Male and Female Rats
por: Towner, Trevor T., et al.
Publicado: (2022)

Uremia
por: Low, J. H.
Publicado: (1883)

Vocalization Induced CFos Expression in Marmoset Cortex
por: Miller, Cory T., et al.
Publicado: (2010)

Mehr weibliche CFOs braucht das Land
por: Hiebl, Martin R. W.
Publicado: (2020)

Uric acid therapy for vasculoprotection in acute ischemic stroke
por: Amaro, Sergi, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_mv9s6sesvbg8haijtq7bqurta1