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Invasive Candida pneumonia, in association with Candida esophagitis and gastritis, in a presumably immunocompetent patient

Candida pneumonia remains a difficult diagnosis and is most common in immunocompromised individuals. It has been rarely reported in immunocompetent individuals. We present a case of unsuspected Candida pneumonia associated with Candida esophagitis and gastritis discovered on postmortem examination i...

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Autores principales: Jackson, Devon, Coke, Lamarque, Fernandez, Kamilah, Brister, Kathriel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hospital Universitário da Universidade de São Paulo 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10546647/
https://www.ncbi.nlm.nih.gov/pubmed/37795249
http://dx.doi.org/10.4322/acr.2023.443
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author Jackson, Devon
Coke, Lamarque
Fernandez, Kamilah
Brister, Kathriel
author_facet Jackson, Devon
Coke, Lamarque
Fernandez, Kamilah
Brister, Kathriel
author_sort Jackson, Devon
collection PubMed
description Candida pneumonia remains a difficult diagnosis and is most common in immunocompromised individuals. It has been rarely reported in immunocompetent individuals. We present a case of unsuspected Candida pneumonia associated with Candida esophagitis and gastritis discovered on postmortem examination in a presumably immunocompetent patient. The patient was a 71-year-old male who presented with chest pain and was subsequently found to have a myocardial infarction treated with angioplasty and drug-eluting stent placement. The patient’s recovery was complicated by pneumonia refractory to antibiotics, and he went on to experience acute hypoxic respiratory failure, sepsis, disseminated intravascular coagulation (DIC), and ultimately expired. Autopsy revealed evidence of myocardial infarction as well as unsuspected Candida albicans pneumonia, esophagitis, and gastritis. Our case highlights how a presumably immunocompetent individual can develop this infection and how Candida esophagitis and Candida gastritis can be seen in association with Candida pneumonia. Due to the difficulty in diagnosing Candida pneumonia antemortem, autopsies provide a key opportunity to better understand these cases and the factors that may contribute to their development.
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spelling pubmed-105466472023-10-04 Invasive Candida pneumonia, in association with Candida esophagitis and gastritis, in a presumably immunocompetent patient Jackson, Devon Coke, Lamarque Fernandez, Kamilah Brister, Kathriel Autops Case Rep Autopsy Case Report Candida pneumonia remains a difficult diagnosis and is most common in immunocompromised individuals. It has been rarely reported in immunocompetent individuals. We present a case of unsuspected Candida pneumonia associated with Candida esophagitis and gastritis discovered on postmortem examination in a presumably immunocompetent patient. The patient was a 71-year-old male who presented with chest pain and was subsequently found to have a myocardial infarction treated with angioplasty and drug-eluting stent placement. The patient’s recovery was complicated by pneumonia refractory to antibiotics, and he went on to experience acute hypoxic respiratory failure, sepsis, disseminated intravascular coagulation (DIC), and ultimately expired. Autopsy revealed evidence of myocardial infarction as well as unsuspected Candida albicans pneumonia, esophagitis, and gastritis. Our case highlights how a presumably immunocompetent individual can develop this infection and how Candida esophagitis and Candida gastritis can be seen in association with Candida pneumonia. Due to the difficulty in diagnosing Candida pneumonia antemortem, autopsies provide a key opportunity to better understand these cases and the factors that may contribute to their development. Hospital Universitário da Universidade de São Paulo 2023-08-07 /pmc/articles/PMC10546647/ /pubmed/37795249 http://dx.doi.org/10.4322/acr.2023.443 Text en Copyright © 2023 The Author(s). https://creativecommons.org/licenses/by/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Autopsy Case Report
Jackson, Devon
Coke, Lamarque
Fernandez, Kamilah
Brister, Kathriel
Invasive Candida pneumonia, in association with Candida esophagitis and gastritis, in a presumably immunocompetent patient
title Invasive Candida pneumonia, in association with Candida esophagitis and gastritis, in a presumably immunocompetent patient
title_full Invasive Candida pneumonia, in association with Candida esophagitis and gastritis, in a presumably immunocompetent patient
title_fullStr Invasive Candida pneumonia, in association with Candida esophagitis and gastritis, in a presumably immunocompetent patient
title_full_unstemmed Invasive Candida pneumonia, in association with Candida esophagitis and gastritis, in a presumably immunocompetent patient
title_short Invasive Candida pneumonia, in association with Candida esophagitis and gastritis, in a presumably immunocompetent patient
title_sort invasive candida pneumonia, in association with candida esophagitis and gastritis, in a presumably immunocompetent patient
topic Autopsy Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10546647/
https://www.ncbi.nlm.nih.gov/pubmed/37795249
http://dx.doi.org/10.4322/acr.2023.443
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