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Evaluation of prothrombotic risk of two PROC hotspot mutations (Arg189Trp and Lys193del) in Chinese population: a retrospective study

BACKGROUND: R189W and K193del of protein C (PC) were hotspot mutations in Chinese population with venous thromboembolism (VTE), but almost two-thirds of patients with above mutations coexisting with other genetically or aquiredly prothrombotic risk factors. The aim of this study is to clarify the in...

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Detalles Bibliográficos
Autores principales: Li, Lei, Li, Jian, Wu, Xi, Wu, Wenman, Ding, Qiulan, Qian, Baohua, Wang, Xuefeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10546776/
https://www.ncbi.nlm.nih.gov/pubmed/37789321
http://dx.doi.org/10.1186/s12959-023-00548-6