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Identification of methylation-regulated genes modulating microglial phagocytosis in hyperhomocysteinemia-exacerbated Alzheimer’s disease

BACKGROUND: Hyperhomocysteinemia (HHcy) has been linked to development of Alzheimer’s disease (AD) neuropathologically characterized by the accumulation of amyloid β (Aβ). Microglia (MG) play a crucial role in uptake of Aβ fibrils, and its dysfunction worsens AD. However, the effect of HHcy on MG Aβ...

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Detalles Bibliográficos
Autores principales:	Wang, Xianwei, Liu, Lu, Jiang, Xiaohua, Saredy, Jason, Xi, Hang, Cueto, Ramon, Sigler, Danni, Khan, Mohsin, Wu, Sheng, Ji, Yong, Snyder, Nathaniel W., Hu, Wenhui, Yang, Xiaofeng, Wang, Hong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2023
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10546779/ https://www.ncbi.nlm.nih.gov/pubmed/37789414 http://dx.doi.org/10.1186/s13195-023-01311-9

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