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Molecular Characterization of HER2-Low Invasive Breast Carcinoma by Quantitative RT-PCR Using Oncotype DX Assay
BACKGROUND: HER2 immunohistochemistry (IHC) reproducibility is suboptimal for HER-low cases (IHC 1+ or 2+). METHODS: The Yale cohort included 214 stages I-II estrogen receptor positive breast cancers with IHC scores 0, 1+, and 2+ and routine Oncotype DX Recurrence Score (RS) results. The Exact Scien...
Autores principales: | Lin, Hao-Kuen, Can, Thuy, Kahn, Adriana, Flannery, Cynthia A, Hoag, Jess, Akkunuri, Alekhya, Bailey, Helen, Baehner, Rick, Pusztai, Lajos, Rozenblit, Mariya |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10546821/ https://www.ncbi.nlm.nih.gov/pubmed/37656608 http://dx.doi.org/10.1093/oncolo/oyad249 |
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