Advances in the Study of Plant-Derived Vesicle-Like Nanoparticles in Inflammatory Diseases

All humans are universally affected by inflammatory diseases, and there is an urgent need to identify new anti-inflammatory drugs with good therapeutic benefits and minimal side effects to the organism. Recently, it has been found that plant-derived vesicle-like nanoparticles (PDVLNs) have good bioc...

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Detalles Bibliográficos
Autores principales: Tan, Xuejun, Xu, Yukun, Zhou, Sirui, Pan, Mingyue, Cao, Yue, Cai, Xiuping, Zhao, Qing, Zhao, Kewei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2023
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10547002/
https://www.ncbi.nlm.nih.gov/pubmed/37795493
http://dx.doi.org/10.2147/JIR.S421124
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author Tan, Xuejun
Xu, Yukun
Zhou, Sirui
Pan, Mingyue
Cao, Yue
Cai, Xiuping
Zhao, Qing
Zhao, Kewei
author_facet Tan, Xuejun
Xu, Yukun
Zhou, Sirui
Pan, Mingyue
Cao, Yue
Cai, Xiuping
Zhao, Qing
Zhao, Kewei
author_sort Tan, Xuejun
collection PubMed
description All humans are universally affected by inflammatory diseases, and there is an urgent need to identify new anti-inflammatory drugs with good therapeutic benefits and minimal side effects to the organism. Recently, it has been found that plant-derived vesicle-like nanoparticles (PDVLNs) have good biocompatibility, with their active ingredients exhibiting good therapeutic effects on inflammation. They can also be used as drug carriers for targeted delivery of anti-inflammatory drugs. Therefore, PDVLNs represent a popular research area for novel anti-inflammatory drugs. This paper details the origin, biological functions, isolation and purification, and identification of PDVLNs, as well as the therapeutic effects of their intrinsic bioactive components on inflammatory diseases. It also introduces their targets as drug carriers to facilitate the development and application of PDVLNs anti-inflammatory drugs.
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spelling pubmed-105470022023-10-04 Advances in the Study of Plant-Derived Vesicle-Like Nanoparticles in Inflammatory Diseases Tan, Xuejun Xu, Yukun Zhou, Sirui Pan, Mingyue Cao, Yue Cai, Xiuping Zhao, Qing Zhao, Kewei J Inflamm Res Review All humans are universally affected by inflammatory diseases, and there is an urgent need to identify new anti-inflammatory drugs with good therapeutic benefits and minimal side effects to the organism. Recently, it has been found that plant-derived vesicle-like nanoparticles (PDVLNs) have good biocompatibility, with their active ingredients exhibiting good therapeutic effects on inflammation. They can also be used as drug carriers for targeted delivery of anti-inflammatory drugs. Therefore, PDVLNs represent a popular research area for novel anti-inflammatory drugs. This paper details the origin, biological functions, isolation and purification, and identification of PDVLNs, as well as the therapeutic effects of their intrinsic bioactive components on inflammatory diseases. It also introduces their targets as drug carriers to facilitate the development and application of PDVLNs anti-inflammatory drugs. Dove 2023-09-29 /pmc/articles/PMC10547002/ /pubmed/37795493 http://dx.doi.org/10.2147/JIR.S421124 Text en © 2023 Tan et al. https://creativecommons.org/licenses/by-nc/3.0/This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution – Non Commercial (unported, v3.0) License (http://creativecommons.org/licenses/by-nc/3.0/ (https://creativecommons.org/licenses/by-nc/3.0/) ). By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. For permission for commercial use of this work, please see paragraphs 4.2 and 5 of our Terms (https://www.dovepress.com/terms.php).
spellingShingle Review
Tan, Xuejun
Xu, Yukun
Zhou, Sirui
Pan, Mingyue
Cao, Yue
Cai, Xiuping
Zhao, Qing
Zhao, Kewei
Advances in the Study of Plant-Derived Vesicle-Like Nanoparticles in Inflammatory Diseases
title Advances in the Study of Plant-Derived Vesicle-Like Nanoparticles in Inflammatory Diseases
title_full Advances in the Study of Plant-Derived Vesicle-Like Nanoparticles in Inflammatory Diseases
title_fullStr Advances in the Study of Plant-Derived Vesicle-Like Nanoparticles in Inflammatory Diseases
title_full_unstemmed Advances in the Study of Plant-Derived Vesicle-Like Nanoparticles in Inflammatory Diseases
title_short Advances in the Study of Plant-Derived Vesicle-Like Nanoparticles in Inflammatory Diseases
title_sort advances in the study of plant-derived vesicle-like nanoparticles in inflammatory diseases
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10547002/
https://www.ncbi.nlm.nih.gov/pubmed/37795493
http://dx.doi.org/10.2147/JIR.S421124
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