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Antioxioxidant and antiapoptotic effects of Thymosin β4 in Aβ-induced SH-SY5Y cells via the 5-HTR1A/ERK axis

Alzheimer’s disease (AD) is a common amnestic cognitive impairment characterised by β-amyloid (Aβ) plaques deposit in the brain of the elderly. AD is a yet incurable disease due to its unknown exact pathogenesis and unavailability of effective remedies in clinical application. Thymosin β4 (Tβ4) is a...

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Detalles Bibliográficos
Autores principales: Zhang, Gui-Hong, Chin, Kai Ling, Yan, Shi-Yan, Pare, Rahmawati
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10547165/
https://www.ncbi.nlm.nih.gov/pubmed/37788276
http://dx.doi.org/10.1371/journal.pone.0287817