Cargando…

Broad functional profiling of fission yeast proteins using phenomics and machine learning

Many proteins remain poorly characterized even in well-studied organisms, presenting a bottleneck for research. We applied phenomics and machine-learning approaches with Schizosaccharomyces pombe for broad cues on protein functions. We assayed colony-growth phenotypes to measure the fitness of delet...

Descripción completa

Detalles Bibliográficos
Autores principales: Rodríguez-López, María, Bordin, Nicola, Lees, Jon, Scholes, Harry, Hassan, Shaimaa, Saintain, Quentin, Kamrad, Stephan, Orengo, Christine, Bähler, Jürg
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10547477/
https://www.ncbi.nlm.nih.gov/pubmed/37787768
http://dx.doi.org/10.7554/eLife.88229