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FAM129A promotes self-renewal and maintains invasive status via stabilizing the Notch intracellular domain in glioma stem cells
BACKGROUND: Glioma stem cells (GSCs) are a subpopulation of tumor cells with self-renewal and tumorigenic capabilities in glioblastomas (GBMs). Diffuse infiltration of GSCs facilitates tumor progression and frustrates efforts at effective treatment. Further compounding this situation is the currentl...
Autores principales: | Liu, Guohao, Zhang, Po, Chen, Sui, Chen, Zirong, Qiu, Yanmei, Peng, Peng, Huang, Wenda, Cheng, Fangling, Zhang, Yang, Li, Huan, Xiao, Qungen, Mao, Feng, Wang, Baofeng, Jiang, Xiaobing, Wan, Feng, Guo, Dongsheng, Yu, Xingjiang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10547521/ https://www.ncbi.nlm.nih.gov/pubmed/37083136 http://dx.doi.org/10.1093/neuonc/noad079 |
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