Cargando…

FAM129A promotes self-renewal and maintains invasive status via stabilizing the Notch intracellular domain in glioma stem cells

BACKGROUND: Glioma stem cells (GSCs) are a subpopulation of tumor cells with self-renewal and tumorigenic capabilities in glioblastomas (GBMs). Diffuse infiltration of GSCs facilitates tumor progression and frustrates efforts at effective treatment. Further compounding this situation is the currentl...

Descripción completa

Detalles Bibliográficos
Autores principales:	Liu, Guohao, Zhang, Po, Chen, Sui, Chen, Zirong, Qiu, Yanmei, Peng, Peng, Huang, Wenda, Cheng, Fangling, Zhang, Yang, Li, Huan, Xiao, Qungen, Mao, Feng, Wang, Baofeng, Jiang, Xiaobing, Wan, Feng, Guo, Dongsheng, Yu, Xingjiang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2023
Materias:	Basic and Translational Investigations
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10547521/ https://www.ncbi.nlm.nih.gov/pubmed/37083136 http://dx.doi.org/10.1093/neuonc/noad079

Ejemplares similares

Immunogenic Cell Death Enhances Immunotherapy of Diffuse Intrinsic Pontine Glioma: From Preclinical to Clinical Studies
por: Liu, Guohao, et al.
Publicado: (2022)

Tenascin-C can Serve as an Indicator for the Immunosuppressive Microenvironment of Diffuse Low-Grade Gliomas
por: Zhang, Po, et al.
Publicado: (2022)

Hypoxia-induced HMGB1 promotes glioma stem cells self-renewal and tumorigenicity via RAGE
por: Ye, Cuifang, et al.
Publicado: (2022)

LRIG2 promotes glioblastoma progression by modulating innate antitumor immunity through macrophage infiltration and polarization
por: Hu, Jinyang, et al.
Publicado: (2022)

High expression of TXNDC11 indicated unfavorable prognosis of glioma
por: Peng, Peng, et al.
Publicado: (2021)

TGFBI secreted by tumor-associated macrophages promotes glioblastoma stem cell-driven tumor growth via integrin αvβ5-Src-Stat3 signaling
por: Peng, Peng, et al.
Publicado: (2022)

LRIG2 promotes the proliferation and cell cycle progression of glioblastoma cells in vitro and in vivo through enhancing PDGFRβ signaling
por: Xiao, Qungen, et al.
Publicado: (2018)

LRIG2 promotes the proliferation and cell cycle progression of glioblastoma cells in vitro and in vivo through enhancing PDGFRβ signaling
por: Xiao, Qungen, et al.
Publicado: (2019)

LRIG2 promotes the proliferation and cell cycle progression of glioblastoma cells in vitro and in vivo through enhancing PDGFRβ signaling
por: Xiao, Qungen, et al.
Publicado: (2022)

The Prognostic and Therapeutic Potential of LRIG3 and Soluble LRIG3 in Glioblastoma
por: Cheng, Fangling, et al.
Publicado: (2019)

Corrigendum: The Prognostic and Therapeutic Potential of LRIG3 and Soluble LRIG3 in Glioblastoma
por: Cheng, Fangling, et al.
Publicado: (2020)

Deficiency of FAM3D (Family With Sequence Similarity 3, Member D), A Novel Chemokine, Attenuates Neutrophil Recruitment and Ameliorates Abdominal Aortic Aneurysm Development
por: He, Li, et al.
Publicado: (2018)

PCBP1 regulates LIFR through FAM3C to maintain breast cancer stem cell self-renewal and invasiveness
por: Streitfeld, William S., et al.
Publicado: (2023)

Ras-transformation reduce FAM20C expression and osteopontin phosphorylation
por: Schytte, Gitte N., et al.
Publicado: (2020)

Glioblastoma Immunotherapy Targeting the Innate Immune Checkpoint CD47-SIRPα Axis
por: Hu, Jinyang, et al.
Publicado: (2020)

Establishment and characteristics of GWH04, a new primary human glioblastoma cell line
por: Cheng, Fangling, et al.
Publicado: (2022)

FAM129B is a novel regulator of Wnt/β-catenin signal transduction in melanoma cells
por: Conrad, Willliam, et al.
Publicado: (2013)

FAM129B, an antioxidative protein, reduces chemosensitivity by competing with Nrf2 for Keap1 binding
por: Cheng, Kai-Chun, et al.
Publicado: (2019)

Soluble LRIG2 Ectodomain Is Released from Glioblastoma Cells and Promotes the Proliferation and Inhibits the Apoptosis of Glioblastoma Cells In Vitro and In Vivo in a Similar Manner to the Full-Length LRIG2
por: Xiao, Qungen, et al.
Publicado: (2014)

LncRNA FAM181A-AS1 promotes gliomagenesis by sponging miR-129-5p and upregulating ZRANB2
por: Jiang, Xin, et al.
Publicado: (2020)

Novel role of pancreatic differentiation 2 in facilitating self-renewal and drug resistance of pancreatic cancer stem cells
por: Vaz, A P, et al.
Publicado: (2014)

γ-Secretase inhibitor enhances antitumour effect of radiation in Notch-expressing lung cancer
por: Mizugaki, H, et al.
Publicado: (2012)

[Retracted] FAM172A induces S phase arrest of HepG2 cells via Notch 3
por: Feng, Zhiqiang, et al.
Publicado: (2023)

Maintaining Success for Patients With Dilated Cardiomyopathy and Remission of Heart Failure
por: Halliday, Brian P., et al.
Publicado: (2022)

Implication of KRT16, FAM129A and HKDC1 genes as ATF4 regulated components of the integrated stress response
por: Evstafieva, Alexandra G., et al.
Publicado: (2018)

Adipose-derived stem cell exosomes regulate Nrf2/Keap1 in diabetic nephropathy by targeting FAM129B
por: Ren, Peiyao, et al.
Publicado: (2023)

Overexpression of AMPD2 indicates poor prognosis in colorectal cancer patients via the Notch3 signaling pathway
por: Gao, Qi-Zhong, et al.
Publicado: (2020)

Silencing NOTCH signaling causes growth arrest in both breast cancer stem cells and breast cancer cells
por: Suman, S, et al.
Publicado: (2013)

β‐Elemene Selectively Inhibits the Proliferation of Glioma Stem‐Like Cells Through the Downregulation of Notch1
por: Feng, Hai‐bin, et al.
Publicado: (2016)

The epigenetic modifier Fam208a is required to maintain epiblast cell fitness
por: Bhargava, Shohag, et al.
Publicado: (2017)

Camptothecin suppresses NRF2–ARE activity and sensitises hepatocellular carcinoma cells to anticancer drugs
por: Chen, Feng, et al.
Publicado: (2017)

Targeting both Notch and ErbB-2 signalling pathways is required for prevention of ErbB-2-positive breast tumour recurrence
por: Pandya, K, et al.
Publicado: (2011)

MiR-129 blocks estrogen induction of NOTCH signaling activity in breast cancer stem-like cells
por: Xiao, Guodong, et al.
Publicado: (2017)

S645C Point Mutation Suppresses Degradation of EGFR to Promote Progression of Glioblastoma
por: Huang, Wenda, et al.
Publicado: (2022)

The new molecular markers DDIT3, STT3A, ARG2 and FAM129A are not useful in diagnosing thyroid follicular tumors
por: Sigstad, Eva, et al.
Publicado: (2012)

Genomic analyses reveal FAM84B and the NOTCH pathway are associated with the progression of esophageal squamous cell carcinoma
por: Cheng, Caixia, et al.
Publicado: (2016)

Tumours with elevated levels of the Notch and Wnt pathways exhibit efficacy to PF-03084014, a γ-secretase inhibitor, in a preclinical colorectal explant model
por: Arcaroli, J J, et al.
Publicado: (2013)

The HIF-pathway inhibitor NSC-134754 induces metabolic changes and anti-tumour activity while maintaining vascular function
por: Baker, L C J, et al.
Publicado: (2012)

Surgical resection of glioblastomas induces pleiotrophin-mediated self-renewal of glioblastoma stem cells in recurrent tumors
por: Knudsen, Arnon Møldrup, et al.
Publicado: (2021)

FLI-06 Intercepts Notch Signaling And Suppresses The Proliferation And Self-renewal Of Tongue Cancer Cells
por: Gan, Rui-huan, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_d2avi8otlu7g4d0pcgup14tav2