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The BRCA1/BARD1 complex recognizes pre-ribosomal RNA to facilitate homologous recombination

The BRCA1/BARD1 complex plays a key role in the repair of DNA double-strand breaks (DSBs) in both somatic cells and germ cells. However, the underlying molecular mechanism by which this complex mediates DSB repair is not fully understood. Here, we examined the XY body of male germ cells, where DSBs...

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Detalles Bibliográficos
Autores principales: Wu, Duo, Huang, Huang, Chen, Tenglong, Gai, Xiaochen, Li, Qilin, Wang, Chunhui, Yao, Jia, Liu, Yu, Cai, Shang, Yu, Xiaochun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Nature Singapore 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10547766/
https://www.ncbi.nlm.nih.gov/pubmed/37789001
http://dx.doi.org/10.1038/s41421-023-00590-8