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An end-to-end pipeline for succinic acid production at an industrially relevant scale using Issatchenkia orientalis

Microbial production of succinic acid (SA) at an industrially relevant scale has been hindered by high downstream processing costs arising from neutral pH fermentation for over three decades. Here, we metabolically engineer the acid-tolerant yeast Issatchenkia orientalis for SA production, attaining...

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Detalles Bibliográficos
Autores principales:	Tran, Vinh G., Mishra, Somesh, Bhagwat, Sarang S., Shafaei, Saman, Shen, Yihui, Allen, Jayne L., Crosly, Benjamin A., Tan, Shih-I, Fatma, Zia, Rabinowitz, Joshua D., Guest, Jeremy S., Singh, Vijay, Zhao, Huimin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10547785/ https://www.ncbi.nlm.nih.gov/pubmed/37788990 http://dx.doi.org/10.1038/s41467-023-41616-9

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