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In vitro and in vivo characterization of [(64)Cu][Cu(elesclomol)] as a novel theranostic agent for hypoxic solid tumors

PURPOSE: Hypoxic tumors are associated with therapy resistance and poor cancer prognosis, but methods to detect and counter tumor hypoxia remain insufficient. Our purpose was to investigate (64)Cu(II)-elesclomol ([(64)Cu][Cu(ES)]) as a novel theranostic agent for hypoxic tumors, by implementing an i...

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Detalles Bibliográficos
Autores principales: Liu, Tengzhi, Dahle, Maria Aanesland, Lystad, Mathilde Hirsum, Marignol, Laure, Karlsen, Morten, Redalen, Kathrine Røe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10547809/
https://www.ncbi.nlm.nih.gov/pubmed/37382663
http://dx.doi.org/10.1007/s00259-023-06310-4

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