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Protracted complete response after limited checkpoint inhibitor dosing: A case report
Immunotherapy is an important modality in the treatment of many types of malignancy. The optimal duration of treatment with immunotherapy in patients with metastatic malignancies who experience complete responses is not fully understood. Our case demonstrates a protracted complete response in a pati...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10547855/ https://www.ncbi.nlm.nih.gov/pubmed/37799570 http://dx.doi.org/10.1002/ccr3.7793 |
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author | Sember, Quinne Sigal, Darren |
author_facet | Sember, Quinne Sigal, Darren |
author_sort | Sember, Quinne |
collection | PubMed |
description | Immunotherapy is an important modality in the treatment of many types of malignancy. The optimal duration of treatment with immunotherapy in patients with metastatic malignancies who experience complete responses is not fully understood. Our case demonstrates a protracted complete response in a patient with metastatic gastric adenocarcinoma after just three doses of pembrolizumab. This illustrates a need for further research into which patients might have responses such as these and could therefore be spared additional doses of an expensive treatment with many potential side effects. |
format | Online Article Text |
id | pubmed-10547855 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | John Wiley and Sons Inc. |
record_format | MEDLINE/PubMed |
spelling | pubmed-105478552023-10-05 Protracted complete response after limited checkpoint inhibitor dosing: A case report Sember, Quinne Sigal, Darren Clin Case Rep Case Report Immunotherapy is an important modality in the treatment of many types of malignancy. The optimal duration of treatment with immunotherapy in patients with metastatic malignancies who experience complete responses is not fully understood. Our case demonstrates a protracted complete response in a patient with metastatic gastric adenocarcinoma after just three doses of pembrolizumab. This illustrates a need for further research into which patients might have responses such as these and could therefore be spared additional doses of an expensive treatment with many potential side effects. John Wiley and Sons Inc. 2023-10-03 /pmc/articles/PMC10547855/ /pubmed/37799570 http://dx.doi.org/10.1002/ccr3.7793 Text en © 2023 The Authors. Clinical Case Reports published by John Wiley & Sons Ltd. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ (https://creativecommons.org/licenses/by-nc-nd/4.0/) License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made. |
spellingShingle | Case Report Sember, Quinne Sigal, Darren Protracted complete response after limited checkpoint inhibitor dosing: A case report |
title | Protracted complete response after limited checkpoint inhibitor dosing: A case report |
title_full | Protracted complete response after limited checkpoint inhibitor dosing: A case report |
title_fullStr | Protracted complete response after limited checkpoint inhibitor dosing: A case report |
title_full_unstemmed | Protracted complete response after limited checkpoint inhibitor dosing: A case report |
title_short | Protracted complete response after limited checkpoint inhibitor dosing: A case report |
title_sort | protracted complete response after limited checkpoint inhibitor dosing: a case report |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10547855/ https://www.ncbi.nlm.nih.gov/pubmed/37799570 http://dx.doi.org/10.1002/ccr3.7793 |
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