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The maintenance mechanism of hematopoietic stem cell dormancy: role for a subset of macrophages

Hematopoiesis is regulated by crosstalk between long-term repopulating hematopoietic stem cells (LT-HSCs) and supporting niche cells in the bone marrow (BM). Here, we describe the role of KAI1, which is mainly expressed on LT-HSCs and rarely on other hematopoietic stem-progenitor cells (HSPCs), in n...

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Detalles Bibliográficos
Autores principales: Chae, Cheong-Whan, Choi, Gun, Kim, You Ji, Cho, Mingug, Kwon, Yoo-Wook, Kim, Hyo-Soo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society for Biochemistry and Molecular Biology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10547972/
https://www.ncbi.nlm.nih.gov/pubmed/37574807
http://dx.doi.org/10.5483/BMBRep.2023-0092