Fiber deprivation and microbiome-borne curli shift gut bacterial populations and accelerate disease in a mouse model of Parkinson’s disease

Parkinson’s disease (PD) is a neurological disorder characterized by motor dysfunction, dopaminergic neuron loss, and alpha-synuclein (αSyn) inclusions. Many PD risk factors are known, but those affecting disease progression are not. Lifestyle and microbial dysbiosis are candidates in this context....

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Detalles Bibliográficos
Autores principales: Schmit, Kristopher J., Garcia, Pierre, Sciortino, Alessia, Aho, Velma T.E., Pardo Rodriguez, Beatriz, Thomas, Mélanie H., Gérardy, Jean-Jacques, Bastero Acha, Irati, Halder, Rashi, Cialini, Camille, Heurtaux, Tony, Ostahi, Irina, Busi, Susheel B., Grandmougin, Léa, Lowndes, Tuesday, Singh, Yogesh, Martens, Eric C., Mittelbronn, Michel, Buttini, Manuel, Wilmes, Paul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10548091/
https://www.ncbi.nlm.nih.gov/pubmed/37676767
http://dx.doi.org/10.1016/j.celrep.2023.113071

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