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Nanotube breakthroughs: unveiling the potential of carbon nanotubes as a dual therapeutic arsenal for Alzheimer’s disease and brain tumors

Alzheimer’s disease (AD) and brain tumors are debilitating neurological conditions that pose significant challenges in current medical practices. Existing treatment options for AD primarily focus on symptom management, and brain tumors often require aggressive therapeutic approaches. Novel disease-m...

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Autores principales: Elsori, Deena, Rashid, Gowhar, Khan, Nihad Ashraf, Sachdeva, Punya, Jindal, Riya, Kayenat, Falak, Sachdeva, Bhuvi, Kamal, Mohammad Azhar, Babker, Asaad Ma, Fahmy, Sherif Ashraf
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10548133/
https://www.ncbi.nlm.nih.gov/pubmed/37799472
http://dx.doi.org/10.3389/fonc.2023.1265347
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author Elsori, Deena
Rashid, Gowhar
Khan, Nihad Ashraf
Sachdeva, Punya
Jindal, Riya
Kayenat, Falak
Sachdeva, Bhuvi
Kamal, Mohammad Azhar
Babker, Asaad Ma
Fahmy, Sherif Ashraf
author_facet Elsori, Deena
Rashid, Gowhar
Khan, Nihad Ashraf
Sachdeva, Punya
Jindal, Riya
Kayenat, Falak
Sachdeva, Bhuvi
Kamal, Mohammad Azhar
Babker, Asaad Ma
Fahmy, Sherif Ashraf
author_sort Elsori, Deena
collection PubMed
description Alzheimer’s disease (AD) and brain tumors are debilitating neurological conditions that pose significant challenges in current medical practices. Existing treatment options for AD primarily focus on symptom management, and brain tumors often require aggressive therapeutic approaches. Novel disease-modifying strategies and therapeutic agents are urgently needed to address the underlying causes of AD pathogenesis and improve brain tumor management. In recent years, nanoparticles (NPs) have shown promise as valuable tools in diagnosing and managing various brain disorders, including AD. Among these, carbon nanotubes (CNTs) have garnered attention for their unique properties and biomedical potential. Their ability to cross the blood-brain barrier (BBB) with ease opens up new possibilities for targeted drug delivery and neuroprotection. This literature review aims to explore the versatile nature of CNTs, which can be functionalized with various biomolecules or substances due to their sp2 hybridization. This adaptability enables them to specifically target cells and deliver medications under specific environmental conditions. Moreover, CNTs possess an exceptional capacity to penetrate cell membranes, making them valuable tools in the treatment of AD and brain tumors. By delving into the role of CNTs in biomedicine, this review sheds light on their potential in managing AD, offering a glimpse of hope for effective disease-modifying options. Understanding the mechanisms of CNTs’ action and their capabilities in targeting and delivering medication to affected cells will pave the way for innovative therapeutic strategies that can improve the lives of those afflicted with these devastating neurological conditions. The exploration of CNTs as a dual therapeutic arsenal for both brain tumors and Alzheimer’s disease holds great promise and may usher in a new era of effective treatment strategies for these challenging conditions.
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spelling pubmed-105481332023-10-05 Nanotube breakthroughs: unveiling the potential of carbon nanotubes as a dual therapeutic arsenal for Alzheimer’s disease and brain tumors Elsori, Deena Rashid, Gowhar Khan, Nihad Ashraf Sachdeva, Punya Jindal, Riya Kayenat, Falak Sachdeva, Bhuvi Kamal, Mohammad Azhar Babker, Asaad Ma Fahmy, Sherif Ashraf Front Oncol Oncology Alzheimer’s disease (AD) and brain tumors are debilitating neurological conditions that pose significant challenges in current medical practices. Existing treatment options for AD primarily focus on symptom management, and brain tumors often require aggressive therapeutic approaches. Novel disease-modifying strategies and therapeutic agents are urgently needed to address the underlying causes of AD pathogenesis and improve brain tumor management. In recent years, nanoparticles (NPs) have shown promise as valuable tools in diagnosing and managing various brain disorders, including AD. Among these, carbon nanotubes (CNTs) have garnered attention for their unique properties and biomedical potential. Their ability to cross the blood-brain barrier (BBB) with ease opens up new possibilities for targeted drug delivery and neuroprotection. This literature review aims to explore the versatile nature of CNTs, which can be functionalized with various biomolecules or substances due to their sp2 hybridization. This adaptability enables them to specifically target cells and deliver medications under specific environmental conditions. Moreover, CNTs possess an exceptional capacity to penetrate cell membranes, making them valuable tools in the treatment of AD and brain tumors. By delving into the role of CNTs in biomedicine, this review sheds light on their potential in managing AD, offering a glimpse of hope for effective disease-modifying options. Understanding the mechanisms of CNTs’ action and their capabilities in targeting and delivering medication to affected cells will pave the way for innovative therapeutic strategies that can improve the lives of those afflicted with these devastating neurological conditions. The exploration of CNTs as a dual therapeutic arsenal for both brain tumors and Alzheimer’s disease holds great promise and may usher in a new era of effective treatment strategies for these challenging conditions. Frontiers Media S.A. 2023-09-20 /pmc/articles/PMC10548133/ /pubmed/37799472 http://dx.doi.org/10.3389/fonc.2023.1265347 Text en Copyright © 2023 Elsori, Rashid, Khan, Sachdeva, Jindal, Kayenat, Sachdeva, Kamal, Babker and Fahmy https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Oncology
Elsori, Deena
Rashid, Gowhar
Khan, Nihad Ashraf
Sachdeva, Punya
Jindal, Riya
Kayenat, Falak
Sachdeva, Bhuvi
Kamal, Mohammad Azhar
Babker, Asaad Ma
Fahmy, Sherif Ashraf
Nanotube breakthroughs: unveiling the potential of carbon nanotubes as a dual therapeutic arsenal for Alzheimer’s disease and brain tumors
title Nanotube breakthroughs: unveiling the potential of carbon nanotubes as a dual therapeutic arsenal for Alzheimer’s disease and brain tumors
title_full Nanotube breakthroughs: unveiling the potential of carbon nanotubes as a dual therapeutic arsenal for Alzheimer’s disease and brain tumors
title_fullStr Nanotube breakthroughs: unveiling the potential of carbon nanotubes as a dual therapeutic arsenal for Alzheimer’s disease and brain tumors
title_full_unstemmed Nanotube breakthroughs: unveiling the potential of carbon nanotubes as a dual therapeutic arsenal for Alzheimer’s disease and brain tumors
title_short Nanotube breakthroughs: unveiling the potential of carbon nanotubes as a dual therapeutic arsenal for Alzheimer’s disease and brain tumors
title_sort nanotube breakthroughs: unveiling the potential of carbon nanotubes as a dual therapeutic arsenal for alzheimer’s disease and brain tumors
topic Oncology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10548133/
https://www.ncbi.nlm.nih.gov/pubmed/37799472
http://dx.doi.org/10.3389/fonc.2023.1265347
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