MARCH5‐dependent NLRP3 ubiquitination is required for mitochondrial NLRP3‐NEK7 complex formation and NLRP3 inflammasome activation

The NLRP3 inflammasome plays a key role in responding to pathogens, and endogenous damage and mitochondria are intensively involved in inflammasome activation. The NLRP3 inflammasome forms multiprotein complexes and its sequential assembly is important for its activation. Here, we show that NLRP3 is...

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Detalles Bibliográficos
Autores principales: Park, Yeon‐Ji, Dodantenna, Niranjan, Kim, Yonghyeon, Kim, Tae‐Hwan, Lee, Ho‐Soo, Yoo, Young‐Suk, Heo, June, Lee, Jae‐Ho, Kwon, Myung‐Hee, Kang, Ho Chul, Lee, Jong‐Soo, Cho, Hyeseong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10548170/
https://www.ncbi.nlm.nih.gov/pubmed/37575012
http://dx.doi.org/10.15252/embj.2023113481

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