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Metformin Reduces the Progression of Atherogenesis by Regulating the Sestrin2-mTOR Pathway in Obese and Diabetic Rats

OBJECTIVE: In previous research, we found that Sestrin2 has a strong association with plasma atherogenicity and combats the progression of atherogenesis by regulating the AMPK-mTOR pathway. Metformin, an activator of AMPK, is widely used as a first-line therapy for diabetes, but its role in preventi...

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Detalles Bibliográficos
Autores principales:	Sundararajan, Saravanakumar, Jayachandran, Isaivani, Pandey, Gautam Kumar, Venkatesan, Saravanakumar, Rajagopal, Anusha, Gokulakrishnan, Kuppan, Balasubramanyam, Muthuswamy, Mohan, Viswanathan, Manickam, Nagaraj
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Korean Society of Lipidology and Atherosclerosis 2023
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10548184/ https://www.ncbi.nlm.nih.gov/pubmed/37800110 http://dx.doi.org/10.12997/jla.2023.12.3.290

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