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Development and evaluation of nanobody tracers for noninvasive nuclear imaging of the immune-checkpoint TIGIT

INTRODUCTION: T cell Ig and ITIM domain receptor (TIGIT) is a next-generation immune checkpoint predominantly expressed on activated T cells and NK cells, exhibiting an unfavorable prognostic association with various malignancies. Despite the emergence of multiple TIGIT-blocking agents entering clin...

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Detalles Bibliográficos
Autores principales:	Zeven, Katty, De Groof, Timo W.M., Ceuppens, Hannelore, Awad, Robin Maximilian, Ertveldt, Thomas, de Mey, Wout, Meeus, Fien, Raes, Geert, Breckpot, Karine, Devoogdt, Nick
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2023
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10548220/ https://www.ncbi.nlm.nih.gov/pubmed/37799715 http://dx.doi.org/10.3389/fimmu.2023.1268900

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