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Mechanism of Bazhen decoction in the treatment of colorectal cancer based on network pharmacology, molecular docking, and experimental validation

OBJECTIVE: Bazhen Decoction (BZD) is a common adjuvant therapy drug for colorectal cancer (CRC), although its anti-tumor mechanism is unknown. This study aims to explore the core components, key targets, and potential mechanisms of BZD treatment for CRC. METHODS: The Traditional Chinese Medicine Sys...

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Detalles Bibliográficos
Autores principales: Lu, Shuai, Sun, Xibo, Zhou, Zhongbao, Tang, Huazhen, Xiao, Ruixue, Lv, Qingchen, Wang, Bing, Qu, Jinxiu, Yu, Jinxuan, Sun, Fang, Deng, Zhuoya, Tian, Yuying, Li, Cong, Yang, Zhenpeng, Yang, Penghui, Rao, Benqiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10548240/
https://www.ncbi.nlm.nih.gov/pubmed/37799727
http://dx.doi.org/10.3389/fimmu.2023.1235575