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Differences in spinal postures and mobility among adults with Prader-Willi syndrome, essential obesity, and normal-weight individuals

INTRODUCTION: Spinal kinematics/motion are reported to be altered in adolescents and adults with essential obesity, while no information is available in patients with Prader-Willi syndrome so far. The aim of this study was to examine cross-sectionally the characteristics of spinal postures and mobil...

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Autores principales: Bayartai, Munkh-Erdene, Luomajoki, Hannu, Tringali, Gabriella, De Micheli, Roberta, Grugni, Graziano, Sartorio, Alessandro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10548364/
https://www.ncbi.nlm.nih.gov/pubmed/37800136
http://dx.doi.org/10.3389/fendo.2023.1235030
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author Bayartai, Munkh-Erdene
Luomajoki, Hannu
Tringali, Gabriella
De Micheli, Roberta
Grugni, Graziano
Sartorio, Alessandro
author_facet Bayartai, Munkh-Erdene
Luomajoki, Hannu
Tringali, Gabriella
De Micheli, Roberta
Grugni, Graziano
Sartorio, Alessandro
author_sort Bayartai, Munkh-Erdene
collection PubMed
description INTRODUCTION: Spinal kinematics/motion are reported to be altered in adolescents and adults with essential obesity, while no information is available in patients with Prader-Willi syndrome so far. The aim of this study was to examine cross-sectionally the characteristics of spinal postures and mobility in 34 patients with PWS, in 35 age- and sex-matched adults with essential obesity, and in 37 normal-weight individuals. METHODS: Spinal posture and mobility were assessed using a radiation-free back scan, the Idiag M360 (Idiag, Fehraltorf, Switzerland). Differences in spinal posture and mobility between the three groups were determined using a two-way analysis of variance. RESULTS: Adults with Prader-Willi syndrome had greater thoracic kyphosis [difference between groups (Δ) = 9.6(0), 95% CI 3.3(0) to 15.6(0), p = 0.001], less lumbar lordosis (Δ = -6.5(0), 95% CI -12.7(0) to -0.3(0), p = 0.03) as well as smaller lumbar and hip mobility than those with normal weight. DISCUSSION: Although the characteristics of the spine in patients with Prader-Will syndrome appear to be similar to that found in subjects with essential obesity, Prader-Willi syndrome was found to influence lumbar movements more than thoracic mobility. These results provide relevant information about the characteristics of the spine in adults with Prader-Willi syndrome to be taken into careful consideration in the management of spinal conditions. These findings also highlight the importance of considering the musculoskeletal assessment of spinal postures and approaches targeting spinal and hip flexibility in adults with Prader-Willi syndrome.
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spelling pubmed-105483642023-10-05 Differences in spinal postures and mobility among adults with Prader-Willi syndrome, essential obesity, and normal-weight individuals Bayartai, Munkh-Erdene Luomajoki, Hannu Tringali, Gabriella De Micheli, Roberta Grugni, Graziano Sartorio, Alessandro Front Endocrinol (Lausanne) Endocrinology INTRODUCTION: Spinal kinematics/motion are reported to be altered in adolescents and adults with essential obesity, while no information is available in patients with Prader-Willi syndrome so far. The aim of this study was to examine cross-sectionally the characteristics of spinal postures and mobility in 34 patients with PWS, in 35 age- and sex-matched adults with essential obesity, and in 37 normal-weight individuals. METHODS: Spinal posture and mobility were assessed using a radiation-free back scan, the Idiag M360 (Idiag, Fehraltorf, Switzerland). Differences in spinal posture and mobility between the three groups were determined using a two-way analysis of variance. RESULTS: Adults with Prader-Willi syndrome had greater thoracic kyphosis [difference between groups (Δ) = 9.6(0), 95% CI 3.3(0) to 15.6(0), p = 0.001], less lumbar lordosis (Δ = -6.5(0), 95% CI -12.7(0) to -0.3(0), p = 0.03) as well as smaller lumbar and hip mobility than those with normal weight. DISCUSSION: Although the characteristics of the spine in patients with Prader-Will syndrome appear to be similar to that found in subjects with essential obesity, Prader-Willi syndrome was found to influence lumbar movements more than thoracic mobility. These results provide relevant information about the characteristics of the spine in adults with Prader-Willi syndrome to be taken into careful consideration in the management of spinal conditions. These findings also highlight the importance of considering the musculoskeletal assessment of spinal postures and approaches targeting spinal and hip flexibility in adults with Prader-Willi syndrome. Frontiers Media S.A. 2023-09-20 /pmc/articles/PMC10548364/ /pubmed/37800136 http://dx.doi.org/10.3389/fendo.2023.1235030 Text en Copyright © 2023 Bayartai, Luomajoki, Tringali, De Micheli, Grugni and Sartorio https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Endocrinology
Bayartai, Munkh-Erdene
Luomajoki, Hannu
Tringali, Gabriella
De Micheli, Roberta
Grugni, Graziano
Sartorio, Alessandro
Differences in spinal postures and mobility among adults with Prader-Willi syndrome, essential obesity, and normal-weight individuals
title Differences in spinal postures and mobility among adults with Prader-Willi syndrome, essential obesity, and normal-weight individuals
title_full Differences in spinal postures and mobility among adults with Prader-Willi syndrome, essential obesity, and normal-weight individuals
title_fullStr Differences in spinal postures and mobility among adults with Prader-Willi syndrome, essential obesity, and normal-weight individuals
title_full_unstemmed Differences in spinal postures and mobility among adults with Prader-Willi syndrome, essential obesity, and normal-weight individuals
title_short Differences in spinal postures and mobility among adults with Prader-Willi syndrome, essential obesity, and normal-weight individuals
title_sort differences in spinal postures and mobility among adults with prader-willi syndrome, essential obesity, and normal-weight individuals
topic Endocrinology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10548364/
https://www.ncbi.nlm.nih.gov/pubmed/37800136
http://dx.doi.org/10.3389/fendo.2023.1235030
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