Cargando…

In Vivo Imaging of [60]Fullerene-Based Molecular Spherical Nucleic Acids by Positron Emission Tomography

[Image: see text] (18)F-Labeled [60]fullerene-based molecular spherical nucleic acids (MSNAs), consisting of a human epidermal growth factor receptor 2 (HER2) mRNA antisense oligonucleotide sequence with a native phosphodiester and phosphorothioate backbone, were synthesized, site-specifically label...

Descripción completa

Detalles Bibliográficos
Autores principales:	Äärelä, Antti, Auchynnikava, Tatsiana, Moisio, Olli, Liljenbäck, Heidi, Andriana, Putri, Iqbal, Imran, Lehtimäki, Jyrki, Rajander, Johan, Salo, Harri, Roivainen, Anne, Airaksinen, Anu J., Virta, Pasi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2023
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10548468/ https://www.ncbi.nlm.nih.gov/pubmed/37531591 http://dx.doi.org/10.1021/acs.molpharmaceut.3c00370

Ejemplares similares

Controlled Monofunctionalization of Molecular Spherical Nucleic Acids on a Buckminster Fullerene Core
por: Gulumkar, Vijay, et al.
Publicado: (2021)

Synthesis of Site-Specific Antibody–[60]Fullerene–Oligonucleotide Conjugates for Cellular Targeting
por: Äärelä, Antti, et al.
Publicado: (2023)

Evaluation of [(68)Ga]Ga-NODAGA-RGD for PET Imaging of Rat Autoimmune Myocarditis
por: Jahandideh, Arghavan, et al.
Publicado: (2021)

Synthesis of an Azide- and Tetrazine-Functionalized [60]Fullerene and Its Controlled Decoration with Biomolecules
por: Gulumkar, Vijay, et al.
Publicado: (2021)

Development of [(18)F]AmBF(3) Tetrazine for Radiolabeling of Peptides: Preclinical Evaluation and PET Imaging of [(18)F]AmBF(3)-PEG(7)-Tyr(3)-Octreotide in an AR42J Pancreatic Carcinoma Model
por: Otaru, Sofia, et al.
Publicado: (2022)

Noninvasive and Quantitative Monitoring of the Distributions and Kinetics of MicroRNA-Targeting Molecules in Vivo by Positron Emission Tomography
por: Mäkilä, Jussi, et al.
Publicado: (2019)

Expanding the Scope of the Cleavable N-(Methoxy)oxazolidine Linker for the Synthesis of Oligonucleotide Conjugates
por: Aho, Aapo, et al.
Publicado: (2021)

Assembly of Bleomycin Saccharide-Decorated Spherical Nucleic Acids
por: Tähtinen, Ville, et al.
Publicado: (2022)

2-Trifluoromethyl-6-mercurianiline Nucleotide, a Sensitive (19)F NMR Probe for Hg(II)-mediated Base Pairing
por: Aro-Heinilä, Asmo, et al.
Publicado: (2021)

Exploring Alternative Radiolabeling Strategies for Sialic Acid-Binding Immunoglobulin-Like Lectin 9 Peptide: [(68)Ga]Ga- and [(18)F]AlF-NOTA-Siglec-9
por: Moisio, Olli, et al.
Publicado: (2018)

Site-Specific Linking of an Oligonucleotide to Mono- and Bivalent Recombinant Antibodies with SpyCatcher-SpyTag System for Immuno-PCR
por: Kushnarova-Vakal, Anastasiia, et al.
Publicado: (2020)

Vascular adhesion protein-1-targeted PET imaging in autoimmune myocarditis
por: Jahandideh, Arghavan, et al.
Publicado: (2023)

Efficacy and tolerability of folate-aminopterin therapy in a rat focal model of multiple sclerosis
por: Elo, Petri, et al.
Publicado: (2021)

[(68)Ga]Ga-DOTA-Siglec-9 Detects Pharmacodynamic Changes of FAP-Targeted IL2 Variant Immunotherapy in B16-FAP Melanoma Mice
por: Viitanen, Riikka, et al.
Publicado: (2022)

Preclinical Evaluation of (89)Zr-Desferrioxamine-Bexmarilimab, a Humanized Antibody Against Common Lymphatic Endothelial and Vascular Endothelial Receptor-1, in a Rabbit Model of Renal Fibrosis
por: Moisio, Olli, et al.
Publicado: (2023)

Liposomal Spherical Nucleic Acids
por: Banga, Resham J., et al.
Publicado: (2014)

Giant Spherical Cluster with I-C(140) Fullerene Topology**
por: Heinl, Sebastian, et al.
Publicado: (2015)

Exploiting Glutamine Consumption in Atherosclerotic Lesions by Positron Emission Tomography Tracer (2S,4R)-4-(18)F-Fluoroglutamine
por: Palani, Senthil, et al.
Publicado: (2022)

Corrigendum: Exploiting Glutamine Consumption in Atherosclerotic Lesions by Positron Emission Tomography Tracer (2S,4R)-4-(18)F-Fluoroglutamine
por: Palani, Senthil, et al.
Publicado: (2022)

Radiosynthesis and preclinical evaluation of [(68)Ga]Ga-NOTA-folate for PET imaging of folate receptor β-positive macrophages
por: Moisio, Olli, et al.
Publicado: (2020)

Spherical nucleic acids for precision medicine
por: Mirkin, Chad A., et al.
Publicado: (2013)

(68)Ga-DOTA chelate, a novel imaging agent for assessment of myocardial perfusion and infarction detection in a rodent model
por: Autio, Anu, et al.
Publicado: (2019)

Association between [(68)Ga]NODAGA-RGDyK uptake and dynamics of angiogenesis in a human cell-based 3D model
por: Grönman, Maria, et al.
Publicado: (2021)

High folate receptor expression in gliomas can be detected in vivo using folate-based positron emission tomography with high tumor-to-brain uptake ratio divulging potential future targeting possibilities
por: Miner, Maxwell W. G., et al.
Publicado: (2023)

(2S, 4R)-4-[(18)F]Fluoroglutamine for In vivo PET Imaging of Glioma Xenografts in Mice: an Evaluation of Multiple Pharmacokinetic Models
por: Miner, Maxwell WG, et al.
Publicado: (2020)

Design Considerations for RNA Spherical Nucleic Acids (SNAs)
por: Barnaby, Stacey N., et al.
Publicado: (2016)

Intracellular Fate of Spherical Nucleic Acid Nanoparticle Conjugates
por: Wu, Xiaochen A., et al.
Publicado: (2014)

Precision spherical nucleic acids for delivery of anticancer drugs
por: Bousmail, Danny, et al.
Publicado: (2017)

Development of Spherical Nucleic Acids for Prostate Cancer Immunotherapy
por: Qin, Lei, et al.
Publicado: (2020)

Spherical Nucleic Acids with Tailored and Active Protein Coronae
por: Zhang, Wuliang, et al.
Publicado: (2019)

Spherical nucleic acids as an infectious disease vaccine platform
por: Teplensky, Michelle H., et al.
Publicado: (2022)

Zinc Ion-Dependent Peptide Nucleic Acid-Based Artificial Enzyme that Cleaves RNA—Bulge Size and Sequence Dependence
por: Murtola, Merita, et al.
Publicado: (2017)

Comparison of (68)Ga-DOTA-Siglec-9 and (18)F-Fluorodeoxyribose-Siglec-9: Inflammation Imaging and Radiation Dosimetry
por: Virtanen, Helena, et al.
Publicado: (2017)

Amyloid-Targeting PET Tracer [(18)F]Flutemetamol Accumulates in Atherosclerotic Plaques
por: Hellberg, Sanna, et al.
Publicado: (2019)

Spherical nucleic acids: Organized nucleotide aggregates as versatile nanomedicine
por: Song, Yangmeihui, et al.
Publicado: (2022)

Impact of Liposomal Spherical Nucleic Acid Structure on Immunotherapeutic Function
por: Callmann, Cassandra E., et al.
Publicado: (2021)

Pretargeted PET Imaging of trans-Cyclooctene-Modified Porous Silicon Nanoparticles
por: Keinänen, Outi, et al.
Publicado: (2017)

Positron Emission Tomography Imaging of Macrophages in Atherosclerosis with (18)F-GE-180, a Radiotracer for Translocator Protein (TSPO)
por: Hellberg, Sanna, et al.
Publicado: (2018)

Cross-Linked Micellar Spherical Nucleic Acids from Thermoresponsive Templates
por: Banga, Resham J., et al.
Publicado: (2017)

Gene Regulation Using Spherical Nucleic Acids to Treat Skin Disorders
por: Holmes, Thomas R., et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_9m63dbrdp1itl2a5pto5q18cq2