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The interplay between neoantigens and immune cells in sarcomas treated with checkpoint inhibition

INTRODUCTION: Sarcomas are comprised of diverse bone and connective tissue tumors with few effective therapeutic options for locally advanced unresectable and/or metastatic disease. Recent advances in immunotherapy, in particular immune checkpoint inhibition (ICI), have shown promising outcomes in s...

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Detalles Bibliográficos
Autores principales: Anzar, Irantzu, Malone, Brandon, Samarakoon, Pubudu, Vardaxis, Ioannis, Simovski, Boris, Fontenelle, Hugues, Meza-Zepeda, Leonardo A., Stratford, Richard, Keung, Emily Z., Burgess, Melissa, Tawbi, Hussein A., Myklebost, Ola, Clancy, Trevor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10548483/
https://www.ncbi.nlm.nih.gov/pubmed/37799721
http://dx.doi.org/10.3389/fimmu.2023.1226445