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LINC00922 decoys SIRT3 to facilitate the metastasis of colorectal cancer through up-regulation the H3K27 crotonylation of ETS1 promoter

BACKGROUND: Lysine crotonylation (Kcr) is up-regulation in colorectal cancer (CRC) tissues, while its specific contribution remains uncertain. This study aimed to elucidate the role and mechanism of crotonylation on Lys27 of histone H3 (H3K27cr) in facilitating CRC metastasis. METHODS: Immunohistoch...

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Detalles Bibliográficos
Autores principales: Liao, Meijian, Sun, Xiaolin, Zheng, Wendan, Wu, Mengdi, Wang, Yifan, Yao, Jia, Ma, Yu, Gao, Shoucui, Pei, Dongsheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10548613/
https://www.ncbi.nlm.nih.gov/pubmed/37789393
http://dx.doi.org/10.1186/s12943-023-01859-y