Combined Targeting of NAD Biosynthesis and the NAD-dependent Transcription Factor C-terminal Binding Protein as a Promising Novel Therapy for Pancreatic Cancer

Cancer therapies targeting metabolic derangements unique to cancer cells are emerging as a key strategy to address refractory solid tumors such as pancreatic ductal adenocarcinomas (PDAC) that exhibit resistance to extreme nutrient deprivation in the tumor microenvironment. Nicotinamide adenine dinu...

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Detalles Bibliográficos
Autores principales: Dcona, M. Michael, Chougoni, Kranthi Kumar, Dcona, Diana T., West, Jacqueline L., Singh, Sahib J., Ellis, Keith C., Grossman, Steven R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for Cancer Research 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10549224/
https://www.ncbi.nlm.nih.gov/pubmed/37707363
http://dx.doi.org/10.1158/2767-9764.CRC-22-0521

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