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Chirality: a key parameter in chemical probes

Many small molecule bioactive and marketed drugs are chiral. They are often synthesised from commercially available chiral building blocks. However, chirality is sometimes incorrectly assigned by manufacturers with consequences for the end user ranging from: experimental irreproducibility, wasted ti...

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Detalles Bibliográficos
Autores principales: McGown, Andrew, Nafie, Jordan, Otayfah, Mohammed, Hassell-Hart, Storm, Tizzard, Graham J., Coles, Simon J., Banks, Rebecca, Marsh, Graham P., Maple, Hannah J., Kostakis, George E., Proietti Silvestri, Ilaria, Colbon, Paul, Spencer, John
Formato: Online Artículo Texto
Lenguaje:English
Publicado: RSC 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10549247/
https://www.ncbi.nlm.nih.gov/pubmed/37799583
http://dx.doi.org/10.1039/d3cb00082f