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All-optical ultrasound catheter for rapid B-mode oesophageal imaging

All-optical ultrasound (OpUS) is an imaging paradigm that uses light to both generate and receive ultrasound, and has progressed from benchtop to in vivo studies in recent years, demonstrating promise for minimally invasive surgical applications. In this work, we present a rapid pullback imaging cat...

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Autores principales: Lewis-Thompson, India, Zhang, Edward Z., Beard, Paul C., Desjardins, Adrien E., Colchester, Richard J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Optica Publishing Group 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10549740/
https://www.ncbi.nlm.nih.gov/pubmed/37799692
http://dx.doi.org/10.1364/BOE.494878
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author Lewis-Thompson, India
Zhang, Edward Z.
Beard, Paul C.
Desjardins, Adrien E.
Colchester, Richard J.
author_facet Lewis-Thompson, India
Zhang, Edward Z.
Beard, Paul C.
Desjardins, Adrien E.
Colchester, Richard J.
author_sort Lewis-Thompson, India
collection PubMed
description All-optical ultrasound (OpUS) is an imaging paradigm that uses light to both generate and receive ultrasound, and has progressed from benchtop to in vivo studies in recent years, demonstrating promise for minimally invasive surgical applications. In this work, we present a rapid pullback imaging catheter for side-viewing B-mode ultrasound imaging within the upper gastrointestinal tract. The device comprised an ultrasound transmitter configured to generate ultrasound laterally from the catheter and a plano-concave microresonator for ultrasound reception. This imaging probe was capable of generating ultrasound pressures in excess of 1 MPa with corresponding −6 dB bandwidths > 20 MHz. This enabled imaging resolutions as low as 45 µm and 120 µm in the axial and lateral extent respectively, with a corresponding signal-to-noise ratio (SNR) of 42 dB. To demonstrate the potential of the device for clinical imaging, an ex vivo swine oesophagus was imaged using the working channel of a mock endoscope for device delivery. The full thickness of the oesophagus was resolved and several tissue layers were present in the resulting ultrasound images. This work demonstrates the promise for OpUS to provide rapid diagnostics and guidance alongside conventional endoscopy.
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spelling pubmed-105497402023-10-05 All-optical ultrasound catheter for rapid B-mode oesophageal imaging Lewis-Thompson, India Zhang, Edward Z. Beard, Paul C. Desjardins, Adrien E. Colchester, Richard J. Biomed Opt Express Article All-optical ultrasound (OpUS) is an imaging paradigm that uses light to both generate and receive ultrasound, and has progressed from benchtop to in vivo studies in recent years, demonstrating promise for minimally invasive surgical applications. In this work, we present a rapid pullback imaging catheter for side-viewing B-mode ultrasound imaging within the upper gastrointestinal tract. The device comprised an ultrasound transmitter configured to generate ultrasound laterally from the catheter and a plano-concave microresonator for ultrasound reception. This imaging probe was capable of generating ultrasound pressures in excess of 1 MPa with corresponding −6 dB bandwidths > 20 MHz. This enabled imaging resolutions as low as 45 µm and 120 µm in the axial and lateral extent respectively, with a corresponding signal-to-noise ratio (SNR) of 42 dB. To demonstrate the potential of the device for clinical imaging, an ex vivo swine oesophagus was imaged using the working channel of a mock endoscope for device delivery. The full thickness of the oesophagus was resolved and several tissue layers were present in the resulting ultrasound images. This work demonstrates the promise for OpUS to provide rapid diagnostics and guidance alongside conventional endoscopy. Optica Publishing Group 2023-07-11 /pmc/articles/PMC10549740/ /pubmed/37799692 http://dx.doi.org/10.1364/BOE.494878 Text en Published by Optica Publishing Group under the terms of the Creative Commons Attribution 4.0 License. Further distribution of this work must maintain attribution to the author(s) and the published article’s title, journal citation, and DOI. https://creativecommons.org/licenses/by/4.0/ https://creativecommons.org/licenses/by/4.0/
spellingShingle Article
Lewis-Thompson, India
Zhang, Edward Z.
Beard, Paul C.
Desjardins, Adrien E.
Colchester, Richard J.
All-optical ultrasound catheter for rapid B-mode oesophageal imaging
title All-optical ultrasound catheter for rapid B-mode oesophageal imaging
title_full All-optical ultrasound catheter for rapid B-mode oesophageal imaging
title_fullStr All-optical ultrasound catheter for rapid B-mode oesophageal imaging
title_full_unstemmed All-optical ultrasound catheter for rapid B-mode oesophageal imaging
title_short All-optical ultrasound catheter for rapid B-mode oesophageal imaging
title_sort all-optical ultrasound catheter for rapid b-mode oesophageal imaging
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10549740/
https://www.ncbi.nlm.nih.gov/pubmed/37799692
http://dx.doi.org/10.1364/BOE.494878
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