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All-optical ultrasound catheter for rapid B-mode oesophageal imaging
All-optical ultrasound (OpUS) is an imaging paradigm that uses light to both generate and receive ultrasound, and has progressed from benchtop to in vivo studies in recent years, demonstrating promise for minimally invasive surgical applications. In this work, we present a rapid pullback imaging cat...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Optica Publishing Group
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10549740/ https://www.ncbi.nlm.nih.gov/pubmed/37799692 http://dx.doi.org/10.1364/BOE.494878 |
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author | Lewis-Thompson, India Zhang, Edward Z. Beard, Paul C. Desjardins, Adrien E. Colchester, Richard J. |
author_facet | Lewis-Thompson, India Zhang, Edward Z. Beard, Paul C. Desjardins, Adrien E. Colchester, Richard J. |
author_sort | Lewis-Thompson, India |
collection | PubMed |
description | All-optical ultrasound (OpUS) is an imaging paradigm that uses light to both generate and receive ultrasound, and has progressed from benchtop to in vivo studies in recent years, demonstrating promise for minimally invasive surgical applications. In this work, we present a rapid pullback imaging catheter for side-viewing B-mode ultrasound imaging within the upper gastrointestinal tract. The device comprised an ultrasound transmitter configured to generate ultrasound laterally from the catheter and a plano-concave microresonator for ultrasound reception. This imaging probe was capable of generating ultrasound pressures in excess of 1 MPa with corresponding −6 dB bandwidths > 20 MHz. This enabled imaging resolutions as low as 45 µm and 120 µm in the axial and lateral extent respectively, with a corresponding signal-to-noise ratio (SNR) of 42 dB. To demonstrate the potential of the device for clinical imaging, an ex vivo swine oesophagus was imaged using the working channel of a mock endoscope for device delivery. The full thickness of the oesophagus was resolved and several tissue layers were present in the resulting ultrasound images. This work demonstrates the promise for OpUS to provide rapid diagnostics and guidance alongside conventional endoscopy. |
format | Online Article Text |
id | pubmed-10549740 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | Optica Publishing Group |
record_format | MEDLINE/PubMed |
spelling | pubmed-105497402023-10-05 All-optical ultrasound catheter for rapid B-mode oesophageal imaging Lewis-Thompson, India Zhang, Edward Z. Beard, Paul C. Desjardins, Adrien E. Colchester, Richard J. Biomed Opt Express Article All-optical ultrasound (OpUS) is an imaging paradigm that uses light to both generate and receive ultrasound, and has progressed from benchtop to in vivo studies in recent years, demonstrating promise for minimally invasive surgical applications. In this work, we present a rapid pullback imaging catheter for side-viewing B-mode ultrasound imaging within the upper gastrointestinal tract. The device comprised an ultrasound transmitter configured to generate ultrasound laterally from the catheter and a plano-concave microresonator for ultrasound reception. This imaging probe was capable of generating ultrasound pressures in excess of 1 MPa with corresponding −6 dB bandwidths > 20 MHz. This enabled imaging resolutions as low as 45 µm and 120 µm in the axial and lateral extent respectively, with a corresponding signal-to-noise ratio (SNR) of 42 dB. To demonstrate the potential of the device for clinical imaging, an ex vivo swine oesophagus was imaged using the working channel of a mock endoscope for device delivery. The full thickness of the oesophagus was resolved and several tissue layers were present in the resulting ultrasound images. This work demonstrates the promise for OpUS to provide rapid diagnostics and guidance alongside conventional endoscopy. Optica Publishing Group 2023-07-11 /pmc/articles/PMC10549740/ /pubmed/37799692 http://dx.doi.org/10.1364/BOE.494878 Text en Published by Optica Publishing Group under the terms of the Creative Commons Attribution 4.0 License. Further distribution of this work must maintain attribution to the author(s) and the published article’s title, journal citation, and DOI. https://creativecommons.org/licenses/by/4.0/ https://creativecommons.org/licenses/by/4.0/ |
spellingShingle | Article Lewis-Thompson, India Zhang, Edward Z. Beard, Paul C. Desjardins, Adrien E. Colchester, Richard J. All-optical ultrasound catheter for rapid B-mode oesophageal imaging |
title | All-optical ultrasound catheter for rapid B-mode
oesophageal imaging |
title_full | All-optical ultrasound catheter for rapid B-mode
oesophageal imaging |
title_fullStr | All-optical ultrasound catheter for rapid B-mode
oesophageal imaging |
title_full_unstemmed | All-optical ultrasound catheter for rapid B-mode
oesophageal imaging |
title_short | All-optical ultrasound catheter for rapid B-mode
oesophageal imaging |
title_sort | all-optical ultrasound catheter for rapid b-mode
oesophageal imaging |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10549740/ https://www.ncbi.nlm.nih.gov/pubmed/37799692 http://dx.doi.org/10.1364/BOE.494878 |
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