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Dielectric response as a novel marker for ablation lesion quality: Relation to conventional ablation parameters

BACKGROUND: The tissue response viewer (TRV) is a novel marker for ablation lesion quality that aims to classify lesions into transmural or nontransmural lesions (high or low dielectric response, HDR or LDR) using dielectric‐based tissue assessment. The objective of this study was to gain insight in...

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Autores principales: Abeln, Bob G. S., van Dijk, Vincent F., Balt, Jippe C., Wijffels, Maurits C. E. F., Boersma, Lucas V. A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10549823/
https://www.ncbi.nlm.nih.gov/pubmed/37799786
http://dx.doi.org/10.1002/joa3.12907
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author Abeln, Bob G. S.
van Dijk, Vincent F.
Balt, Jippe C.
Wijffels, Maurits C. E. F.
Boersma, Lucas V. A.
author_facet Abeln, Bob G. S.
van Dijk, Vincent F.
Balt, Jippe C.
Wijffels, Maurits C. E. F.
Boersma, Lucas V. A.
author_sort Abeln, Bob G. S.
collection PubMed
description BACKGROUND: The tissue response viewer (TRV) is a novel marker for ablation lesion quality that aims to classify lesions into transmural or nontransmural lesions (high or low dielectric response, HDR or LDR) using dielectric‐based tissue assessment. The objective of this study was to gain insight in the TRV by relating its outcomes to conventional ablation parameters. METHODS: Patients that had repeat ablation for atrial fibrillation with a dielectric imaging‐based mapping system were enrolled. All ablation data were downloaded from the mapping system and analyzed to explore associations between TRV outcomes and other ablation parameters. RESULTS: The cohort included 24 patients, in which 58 pulmonary veins and 8 superior vena cavas were targeted. A total of 388 energy applications were applied, resulting in 639 ablation points. The system classified 36% of ablation points as HDR and 44% as LDR. The system did not provide a dielectric response in 20%. The system's ability to provide a dielectric response was related to longer ablation duration and absence of dragging ablation. HDR (versus LDR) was multivariably associated with longer energy applications, higher mean ablation power, and lower wall thickness. Greater impedance drop was univariably associated with HDR. CONCLUSION: Outcomes of the TRV are associated with conventional ablation parameters (e.g., duration and power) but also local wall thickness. Catheter stability seems important for successful lesion assessment with the TRV. Further reduction of missing outcomes and validation of the tool are warranted before widespread use.
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spelling pubmed-105498232023-10-05 Dielectric response as a novel marker for ablation lesion quality: Relation to conventional ablation parameters Abeln, Bob G. S. van Dijk, Vincent F. Balt, Jippe C. Wijffels, Maurits C. E. F. Boersma, Lucas V. A. J Arrhythm Original Articles BACKGROUND: The tissue response viewer (TRV) is a novel marker for ablation lesion quality that aims to classify lesions into transmural or nontransmural lesions (high or low dielectric response, HDR or LDR) using dielectric‐based tissue assessment. The objective of this study was to gain insight in the TRV by relating its outcomes to conventional ablation parameters. METHODS: Patients that had repeat ablation for atrial fibrillation with a dielectric imaging‐based mapping system were enrolled. All ablation data were downloaded from the mapping system and analyzed to explore associations between TRV outcomes and other ablation parameters. RESULTS: The cohort included 24 patients, in which 58 pulmonary veins and 8 superior vena cavas were targeted. A total of 388 energy applications were applied, resulting in 639 ablation points. The system classified 36% of ablation points as HDR and 44% as LDR. The system did not provide a dielectric response in 20%. The system's ability to provide a dielectric response was related to longer ablation duration and absence of dragging ablation. HDR (versus LDR) was multivariably associated with longer energy applications, higher mean ablation power, and lower wall thickness. Greater impedance drop was univariably associated with HDR. CONCLUSION: Outcomes of the TRV are associated with conventional ablation parameters (e.g., duration and power) but also local wall thickness. Catheter stability seems important for successful lesion assessment with the TRV. Further reduction of missing outcomes and validation of the tool are warranted before widespread use. John Wiley and Sons Inc. 2023-08-03 /pmc/articles/PMC10549823/ /pubmed/37799786 http://dx.doi.org/10.1002/joa3.12907 Text en © 2023 The Authors. Journal of Arrhythmia published by John Wiley & Sons Australia, Ltd on behalf of Japanese Heart Rhythm Society. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ (https://creativecommons.org/licenses/by-nc-nd/4.0/) License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.
spellingShingle Original Articles
Abeln, Bob G. S.
van Dijk, Vincent F.
Balt, Jippe C.
Wijffels, Maurits C. E. F.
Boersma, Lucas V. A.
Dielectric response as a novel marker for ablation lesion quality: Relation to conventional ablation parameters
title Dielectric response as a novel marker for ablation lesion quality: Relation to conventional ablation parameters
title_full Dielectric response as a novel marker for ablation lesion quality: Relation to conventional ablation parameters
title_fullStr Dielectric response as a novel marker for ablation lesion quality: Relation to conventional ablation parameters
title_full_unstemmed Dielectric response as a novel marker for ablation lesion quality: Relation to conventional ablation parameters
title_short Dielectric response as a novel marker for ablation lesion quality: Relation to conventional ablation parameters
title_sort dielectric response as a novel marker for ablation lesion quality: relation to conventional ablation parameters
topic Original Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10549823/
https://www.ncbi.nlm.nih.gov/pubmed/37799786
http://dx.doi.org/10.1002/joa3.12907
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