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Neuroprotective mechanism of salvianolic acid B against cerebral ischemia–reperfusion injury in mice through downregulation of TLR4, p‐p38MAPK, p‐JNK, NF‐κB, and IL‐1β

OBJECTIVE: Tissue injury and inflammation are two potential outcomes of cerebral ischemia–reperfusion (I/R) injury. Salvianolic acid B (Sal B), isolated from the roots of Salvia miltiorrhiza, is one of the major water‐soluble compounds with a wide range of pharmacological effects including antioxida...

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Detalles Bibliográficos
Autores principales: Zheng, Xiu‐fen, Zhang, Xiang‐jian, Dong, Li‐peng, Zhao, Jing‐ru, Zhang, Cong, Chen, Rong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10549825/
https://www.ncbi.nlm.nih.gov/pubmed/37904689
http://dx.doi.org/10.1002/iid3.1030