Molecular detection of Leptospira spp. in small wild rodents from rural areas of São Paulo State, Brazil

BACKGROUND: Leptospirosis represents a One Health issue, affecting humans and animals. This study investigated pathogenic leptospires in small wild rodents in São Paulo, Brazil. METHODS: Kidney samples from 164 rodents underwent qPCR testing, targeting pathogenic Leptospira spp. RESULTS: Thirty-five...

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Detalles Bibliográficos
Autores principales: da Silva, Evelyn Cristine, Fornazari, Felipe, Antunes, João Marcelo Azevedo de Paula, Demoner, Larissa de Castro, de Oliveira, Lucia Helena O’Dwyer, Peres, Marina Gea, Megid, Jane, Langoni, Helio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Sociedade Brasileira de Medicina Tropical - SBMT 2023
Materias:
Short Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10550089/
https://www.ncbi.nlm.nih.gov/pubmed/37792829
http://dx.doi.org/10.1590/0037-8682-0160-2023
Descripción
Sumario:BACKGROUND: Leptospirosis represents a One Health issue, affecting humans and animals. This study investigated pathogenic leptospires in small wild rodents in São Paulo, Brazil. METHODS: Kidney samples from 164 rodents underwent qPCR testing, targeting pathogenic Leptospira spp. RESULTS: Thirty-five animals (21.34%) tested positive, including five rodent species: Akodon montensis (2/21; 9.5%), Necromys lasiurus (1/4; 25%), Oligoryzomys nigripes (24/92; 26.1%), Oligoryzomys flavescens (5/26; 19.2%), and Sooretamys angouya (3/14; 21.4%). Botucatu municipality exhibited the highest prevalence, with 42.5% (20/47) of the animals testing positive. CONCLUSIONS: The presence of Leptospira spp. in wild rodents suggests they may be chronic carriers, contaminating the environment.

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